舒筋活血中药定向透药结合非甾体类抗炎药对肩袖修复术后疗效的前瞻性随机对照研究

发布时间：2019-01-22 10:22

【摘要】：目的:探讨舒筋活血中药定向透药结合非甾体类抗炎药对肩袖修复术后的疗效。方法:选取87例肩袖损伤并行肩袖修复术治疗的患者,随机分为观察组(n=43)和对照组(n=44),对照组术后静脉注射氟比洛芬酯治疗,观察组同时进行舒筋活血中药定向透药治疗,两组均连续治疗5 d,并于术后定期随访6个月。采用疼痛视觉模拟评分(VAS)评价患者疼痛程度;术前及术后3个月、6个月对患者肩关节功能进行评分,观察并记录治疗前后两组患者关节活动范围;统计两组患者治疗期间药物不良反应发生情况。结果:与术后1 d比较,术后3~7 d两组静止相和活动相的VAS评分呈逐渐降低的趋势,术后3 d两组静止相和活动相的VAS评分差异无统计学意义(P0.05),术后5~7 d观察组静止相和活动相VAS评分明显低于对照组(P0.01)。与术前比较,术后3~6个月两组Constant-Murley评分和UCLA评分明显升高(P0.01),前屈上举、体侧外旋活动度明显增大(P0.05或P0.01),体侧内旋达到脊柱高度明显提高,但两组间肩关节功能评分及关节活动度无明显差异(P0.05)。观察组和对照组总不良反应发生率分别为18.18%及13.95%,两组间差异无统计学意义(P0.05)。结论:舒筋活血中药定向透药结合氟比洛芬酯治疗肩袖修复术后患者效果显著,可有效促进患者术后肩关节功能及关节活动范围的恢复,缓解患者术后早期疼痛。
[Abstract]:Objective: to investigate the effect of Shujin Huoxue traditional Chinese medicine combined with non-steroidal anti-inflammatory drugs on rotator cuff repair. Methods: 87 patients with rotator cuff injury treated with rotator cuff repair were randomly divided into observation group (n = 43) and control group (n = 44). The control group was treated with flurbiprofen ester intravenously after operation. The observation group was treated with directional permeation of Shujin Huoxue Chinese medicine for 5 days and followed up regularly for 6 months after operation. The pain degree was evaluated by visual analogue pain score (VAS), the shoulder joint function was evaluated before and after 3 months and 6 months after treatment, and the range of joint motion was observed and recorded before and after treatment. The incidence of adverse drug reactions during treatment was analyzed in two groups. Results: compared with 1 day after operation, the VAS scores of the rest phase and the active phase in the two groups decreased gradually on the 7th day after operation, but there was no significant difference in the VAS score between the two groups on the 3rd day after operation (P0.05). The VAS scores of static and active phase in the observation group were significantly lower than those in the control group on the 7th day after operation (P0.01). Compared with those before operation, the Constant-Murley score and UCLA score of the two groups were significantly increased (P0.01), the lateral rotation activity increased significantly (P0.05 or P0.01), and the lateral rotation reached the spinal height significantly higher than that before operation (P0.01). However, there was no significant difference between the two groups in shoulder function score and joint motion (P0.05). The incidence of total adverse reactions in the observation group and the control group were 18.18% and 13.95%, respectively. There was no significant difference between the two groups (P0.05). Conclusion: directional permeation of Shujin Huoxue Chinese medicine combined with flurbiprofen ester is effective in the treatment of patients with rotator cuff repair. It can effectively promote the recovery of shoulder joint function and the range of joint movement after operation and relieve the early postoperative pain.
【作者单位】：山东大学齐鲁医院(青岛)运动医学科;
【分类号】：R687.4

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