脊柱手术后患者外科手术部位感染及相关危险因素（英文）

发布时间：2019-02-17 16:26

【摘要】：目的外科手术部位感染(SSI)是脊柱手术后常见的并发症之一,与感染发病率增高,治疗时间延长,医疗费用增加,患者预后效果不良有着密不可分的关系。本研究的目的是探索某教学医院患者进行脊柱手术后发生SSI的现状与其相关危险因素。方法采用前瞻性队列研究方法,对2014年6月26日-11月30日该院所有脊柱手术患者进行目标性监测,以美国疾病控制与预防中心(CDC)颁布的指南作为SSI的诊断依据,通过床旁调查与出院后的检查发现SSI病例,使用标准化的数据收集脊柱手术患者术前,术中及术后资料。结果 2014年6月26日—11月30日共监测192例脊柱手术患者,其中7例(3.6%)发生了SSI。通过双变量分析的方法发现切口类型(污染/感染切口)、外科引流、输血与增加SSI风险的密切相关。在192例脊柱手术患者中,120例(62.5%)给予静脉使用预防性抗菌药物,使用周期为2.2(1~9)d,139例(72.4%)使用中成药。结论该研究有助于了解该教学医院脊柱手术后患者SSI发病率,亦为今后进行脊柱手术后患者发生SSI的研究提供有价值的信息。
[Abstract]:Objective infection of (SSI) in surgical site is one of the common complications after spinal surgery, which is closely related to the increase of incidence of infection, the prolongation of treatment time, the increase of medical cost and the poor prognosis of patients. The aim of this study was to explore the status quo and risk factors of SSI in patients undergoing spinal surgery in a teaching hospital. Methods A prospective cohort study was used to conduct targeted surveillance of all patients undergoing spinal surgery from June 26 to November 30, 2014. The guidelines issued by the United States Centers for Disease Control and Prevention (CDC) were used as the basis for the diagnosis of SSI. SSI cases were found by bedside investigation and postdischarge examination. Standardized data were used to collect data before, during and after spinal surgery. Results from June 26 to November 30, 2014, 192 patients underwent spinal surgery, of whom 7 (3.6%) had SSI.. Bivariate analysis showed that the type of incision (contaminated / infected incision), surgical drainage, and blood transfusion were closely associated with increased risk of SSI. Of 192 patients undergoing spinal surgery, 120 (62.5%) were given prophylactic antimicrobial agents, and 139 (72.4%) were given Chinese patent medicine for 2.2 (1 / 9) days. Conclusion this study is helpful to understand the incidence of SSI in patients after spinal surgery in the teaching hospital, and also provides valuable information for the study of SSI in patients undergoing spinal surgery in the future.
【作者单位】：挪威奥斯陆大学医学院健康与社会研究所社区医学与全球健康系;广州中医药大学附属东莞市中医院;挪威公共卫生研究所传染病流行病学系;
【分类号】：R687.3

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