定标活检术评价结肠小息肉活检钳除治疗效果的临床分析
发布时间：2019-03-22 08:31
【摘要】：目的:通过定标活检术评价结肠小息肉活检钳除治疗效果及定标活检在结肠粘膜中的留存情况。方法:取由2012年1月至2014年7月经电子结肠镜检查发现结肠小息肉,且直径均5mm,共120例的患者,予以小息肉粘膜定标后行活检钳除,经过6个月、12个月、18个月的跟踪随访,观察是否有活检后小息肉的复发或残留,并观察定标活检在肠道粘膜的存留时间及存留的效果,分析单次定标成功率、标记在肠道粘膜的存在情况、标记局部黏膜的组织反应及其并发症等情况。同时分析定标活检钳除的并发症等情况。结果:120例患者共有132枚息肉,行定标活检钳除,其中2例出现穿刺后血肿,未行定标及活检钳除,4例息肉定标成功后钳除息肉时将已定标黏膜一并钳除,冲洗后未见定标液残留,且局部黏膜组织较薄,为预防穿孔,未做再次定标,故即时息肉钳除率98.33%,单次定标成功率86.36%,总有效率95.45%。共有114例患者行肠镜复查,其中2例直肠小息肉复发,复发率1.75%,随访超过6个月、12个月、18个月的患者中,定标存在率分别为80.16%、75.40%、74.60%。结论:活检钳钳除结肠小息肉(直径0.5cm)的治疗简便快捷,疗效肯定,用定标活检术评价结肠小息肉活检钳除法更为科学及精确。定标活检术在肠道黏膜中具有标识清晰,留存时间较长,适合肠道疾病的纵向对比研究,临床推广意义较大。
[Abstract]:Objective: to evaluate the therapeutic effect of biopsy and forceps for small polyps of colon and the retention of biopsy in colonic mucosa. Methods: from January 2012 to July 2014, small polyps of colon were found by electronic colonoscopy in 120 patients (5mm in diameter), who underwent biopsy and forceps for 6 months and 12 months after calibrating the mucosa of small polyps. After 18 months of follow-up, the recurrence or residue of small polyps after biopsy was observed, and the retention time and effect of calibration biopsy in intestinal mucosa were observed, the success rate of single calibration was analyzed, and the existence of labeling in intestinal mucosa was analyzed. Local mucosal tissue reaction and its complications were labeled. At the same time, the complications of scaling biopsy forceps were analyzed. Results: 132 polyps were performed in 120 patients, 2 of them had hematoma after puncture, and 4 cases of polyps were removed when the polyps were removed successfully, and 4 cases of polyps were successfully calibrated, and the mucosa was removed simultaneously when the polyps were removed by the forceps, 2 of them had hematoma after puncture, and 4 of them had not been performed biopsy forceps and biopsy forceps. No residual calibration fluid was found after rinsing, and the local mucosal tissue was thinner. In order to prevent perforation and no re-calibration was made, the immediate polyps clamp rate was 98.33%, the success rate of single calibration was 86.36%, and the total effective rate was 95.45%. In 114 patients, the recurrence rate of rectal polyps was 1.75%. The calibration rates were 80.16%, 75.40% and 74.60% respectively in the patients who were followed up for more than 6 months, 12 months and 18 months respectively. The recurrence rates of rectal polyps were 80.16%, 75.40% and 74.60% respectively, and the recurrence rate of rectal polyps was 1.75%. Conclusion: biopsy forceps for the treatment of small polyps of colon (diameter 0.5cm) is simple, rapid and effective. It is more scientific and accurate to evaluate biopsy forceps for small polyps of colon by biopsy. Calibration biopsy has clear mark and long retention time in intestinal mucosa. It is suitable for longitudinal comparative study of intestinal diseases and is of great significance in clinical application.
【学位授予单位】：宁波大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R656.7
本文编号：2445435
[Abstract]:Objective: to evaluate the therapeutic effect of biopsy and forceps for small polyps of colon and the retention of biopsy in colonic mucosa. Methods: from January 2012 to July 2014, small polyps of colon were found by electronic colonoscopy in 120 patients (5mm in diameter), who underwent biopsy and forceps for 6 months and 12 months after calibrating the mucosa of small polyps. After 18 months of follow-up, the recurrence or residue of small polyps after biopsy was observed, and the retention time and effect of calibration biopsy in intestinal mucosa were observed, the success rate of single calibration was analyzed, and the existence of labeling in intestinal mucosa was analyzed. Local mucosal tissue reaction and its complications were labeled. At the same time, the complications of scaling biopsy forceps were analyzed. Results: 132 polyps were performed in 120 patients, 2 of them had hematoma after puncture, and 4 cases of polyps were removed when the polyps were removed successfully, and 4 cases of polyps were successfully calibrated, and the mucosa was removed simultaneously when the polyps were removed by the forceps, 2 of them had hematoma after puncture, and 4 of them had not been performed biopsy forceps and biopsy forceps. No residual calibration fluid was found after rinsing, and the local mucosal tissue was thinner. In order to prevent perforation and no re-calibration was made, the immediate polyps clamp rate was 98.33%, the success rate of single calibration was 86.36%, and the total effective rate was 95.45%. In 114 patients, the recurrence rate of rectal polyps was 1.75%. The calibration rates were 80.16%, 75.40% and 74.60% respectively in the patients who were followed up for more than 6 months, 12 months and 18 months respectively. The recurrence rates of rectal polyps were 80.16%, 75.40% and 74.60% respectively, and the recurrence rate of rectal polyps was 1.75%. Conclusion: biopsy forceps for the treatment of small polyps of colon (diameter 0.5cm) is simple, rapid and effective. It is more scientific and accurate to evaluate biopsy forceps for small polyps of colon by biopsy. Calibration biopsy has clear mark and long retention time in intestinal mucosa. It is suitable for longitudinal comparative study of intestinal diseases and is of great significance in clinical application.
【学位授予单位】：宁波大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R656.7
【参考文献】
相关期刊论文 前2条
1 徐富星,岑戎;Turcot综合征[J];中国实用内科杂志;2000年02期
2 阎晓初,柳凤轩,房殿春,罗元辉,鲁荣;大肠癌细胞周期调控因子表达与微卫星不稳定性的关系[J];中华肿瘤杂志;2000年02期
相关硕士学位论文 前1条
1 赵岚;胃黏膜定标活检技术临床应用价值探讨[D];浙江大学;2008年
，本文编号：2445435
本文链接：https://www.wllwen.com/yixuelunwen/waikelunwen/2445435.html
最近更新
教材专著
