当前位置:主页 > 医学论文 > 外科论文 >

手法松解联合盐酸乙哌立松片口服治疗腰背肌筋膜炎的临床研究

发布时间:2019-04-12 16:21
【摘要】:目的:探讨手法松解联合盐酸乙哌立松片口服治疗腰背肌筋膜炎的临床疗效。方法:将60例腰背肌筋膜炎患者随机分为观察组和对照组,每组30例。观察组采用手法松解联合盐酸乙哌立松片口服治疗,对照组采用芬必得布洛芬缓释胶囊加盐酸乙哌立松片口服治疗。治疗前后分别采用视觉模拟评分量表(visual analogue scale,VAS)和Oswestry功能障碍指数(Oswestry disability index,ODI)对患者腰背部疼痛和腰椎功能进行评估。治疗结束后即根据ODI改善率评价疗效,并随访观察2组患者临床复发情况,记录复发时间。结果:治疗前2组患者VAS评分和ODI评分组间比较,差异均无统计学意义[(7.3±0.9)分,(7.2±1.1)分;t=0.381,P=0.352;(40.4±4.7)分,(39.9±3.5)分;t=0.499,P=0.309]。治疗结束后2组患者VAS评分和ODI评分均较治疗前降低[(7.3±0.9)分,(1.5±0.6)分;t=28.987,P=0.000;(7.2±1.1)分,(1.9±0.8)分;t=21.399,P=0.000;(40.4±4.7)分,(11.6±2.9)分;t=28.665,P=0.000;(39.9±3.5)分,(13.9±2.9)分;t=31.456,P=0.000];且观察组VAS评分和ODI评分均低于对照组[(1.5±0.6)分,(1.9±0.8)分;t=2.633,P=0.005;(11.6±2.9)分,(13.9±2.9)分;t=-3.107,P=0.001]。根据ODI改善率评价疗效,观察组优8例、良22例;对照组优1例、良27例、可2例;观察组疗效优于对照组(Z=-2.793,P=0.005)。60例患者均获随访,随访时间12~36个月,中位数22个月。60例患者均出现复发;治疗结束至症状复发的时间观察组(17.1±7.5)个月,对照组(12.2±6.5)个月;观察组复发较对照组晚(t=2.764,P=0.004)。结论:手法松解联合盐酸乙哌立松片口服治疗腰背肌筋膜炎,可有效缓解疼痛、改善腰椎功能,疗效优于芬必得布洛芬缓释胶囊加盐酸乙哌立松片口服,且更有利于延缓复发。
[Abstract]:Objective: to investigate the clinical effect of manipulation relaxation combined with epiperisone hydrochloride tablets in the treatment of lumbar back fasciitis. Methods: sixty patients with lumbar dorsum fasciitis were randomly divided into observation group and control group with 30 cases in each group. The control group was treated with Fenbid ibuprofen sustained-release capsule and epiperisone hydrochloride tablets orally. The patients' lumbar back pain and lumbar function were evaluated by visual analogue scale (visual analogue scale,VAS) and Oswestry dysfunction index (Oswestry disability index,ODI) before and after treatment. After the treatment, the curative effect was evaluated according to the improvement rate of ODI, and the clinical recurrence of the two groups was observed and the recurrence time was recorded. Results: there was no significant difference in VAS score and ODI score between the two groups before treatment [(7.3 卤0.9), (7.2 卤1.1); t = 0.381, P = 0.352; (40.4 卤4.7), (39.9 卤3.5); T = 0.499, P = 0.309]. After treatment, the scores of VAS and ODI in the two groups decreased [(7.3 卤0.9), (1.5 卤0.6); (28.987, P < 0.001); (7.2 卤1.1), (1.9 卤0.8); (21.399, P < 0.001); (40.4 卤4.7,11.6 卤2.9,28.665, P < 0.001; 39.9 卤3.5,13.9 卤2.9; t = 31.456, P = 0.000); The scores of VAS and ODI in the observation group were lower than those in the control group [(1. 5 卤0. 6), (1. 9 卤0. 8); t = 2.63, P < 0. 05; (11.6 卤2. 9), (13.9 卤2. 9); t = 3. 107, P < 0. 001]. According to the improvement rate of ODI, 8 cases were excellent in the observation group, 22 cases were good in the observation group, 1 case was excellent in the control group, 27 cases were good and 2 cases were fair. The curative effect of the observation group was better than that of the control group (Z = 2.793, P < 0.005). 60 patients were followed up for 12 months for 36 months with a median of 22 months. The time from the end of treatment to the recurrence of symptoms was (17.1 卤7.5) months in the observation group and (12.2 卤6.5) months in the control group, and the recurrence time in the observation group was later than that in the control group (t = 2.764, P = 0.004). Conclusion: manual relaxation combined with epiperisone hydrochloride tablets can effectively relieve pain and improve lumbar spine function, which is better than Fenbid ibuprofen sustained-release capsule and epiperisone hydrochloride tablets oral, and is more beneficial to delay recurrence.
【作者单位】: 中国中医科学院望京医院;
【分类号】:R686.3

【相似文献】

相关期刊论文 前10条

1 付崇铭,李波,郭瑞臣;反相高效液相色谱法测定盐酸乙哌立松片剂的含量[J];中国现代应用药学;2001年01期

2 史爱欣,李可欣,刘蕾,李扬,赫广威,孙春华,宋友华;液相色谱-电喷雾质谱联用测定人血浆中盐酸乙哌立松的浓度[J];药物分析杂志;2002年01期

3 谢宁,曹师锋,王诗波,宋滇文,何海龙,贾连顺;盐酸乙哌立松治疗颈肩痛腰背痛临床疗效评价[J];中国矫形外科杂志;2000年10期

4 张晓景,余翠琴;盐酸乙哌立松治疗肌收缩型头痛[J];浙江中医学院学报;2005年05期

5 刘鹏;;盐酸乙哌立松(Eperisone Hydrochloride)[J];国外医药.合成药.生化药.制剂分册;1988年01期

6 刘彩娜;刘彩玲;李林林;张雪琴;孙艳芳;王中华;张新宽;;盐酸乙哌立松片不良反应1例[J];中国民康医学;2014年07期

7 魏欣,丁黎,高家敏,李君,张胜强,沈建平,张银娣;盐酸乙哌立松片在健康人体内的药代动力学及生物等效性[J];药学学报;2004年04期

8 程彩芹,卢家风,魏文华;口服盐酸乙哌立松片引起疱疹性皮肤损害1例[J];中国医院药学杂志;2005年06期

9 曹高忠;滕红林;吴春雷;刘爱月;吴云刚;吴剑静;;盐酸乙哌立松联合塞来昔布治疗颈肩腰背痛75例疗效分析[J];中国临床药学杂志;2007年05期

10 宋友华,史爱欣,宋琳,李可欣,刘蕾,李扬,赫广威,孙春华;国产盐酸乙哌立松片剂人体生物等效性研究[J];中国药学杂志;2000年03期

相关会议论文 前2条

1 傅厚道;张晋;;中药熏蒸结合盐酸乙哌立松对脑卒中后肌张力增高的临床观察[A];2013浙江省物理医学与康复学学术年会暨第八届浙江省康复医学发展论坛论文集[C];2013年

2 彭丽滢;赵斌;;以嗜睡、血小板减少为首发表现的药物所致横纹肌溶解综合征一例[A];中华医学会急诊医学分会第十六次全国急诊医学学术年会论文集[C];2013年



本文编号:2457172

资料下载
论文发表

本文链接:https://www.wllwen.com/yixuelunwen/waikelunwen/2457172.html


Copyright(c)文论论文网All Rights Reserved | 网站地图 |

版权申明:资料由用户72559***提供,本站仅收录摘要或目录,作者需要删除请E-mail邮箱bigeng88@qq.com