医用硫酸钙治疗创伤性骨折的早期临床疗效评估

发布时间：2019-04-23 15:18

【摘要】：目的观察医用硫酸钙治疗创伤性骨折的早期临床X线表现,评价其应用特点。方法2014年9月至2016年1月,医用硫酸钙治疗创伤性骨折23例;男17例,女6例;年龄20~71岁,平均41.6岁。术后即刻、1、2、4、6、8周、3、6个月依X线片计算医用硫酸钙降解率。结果术后1周,约69%残留;2周,约53%残留;4周,约26%残留;6周,约7%残留;8周,未见明确显影。骨痂初现时间为3~9周,平均(6.5±1.6)周,骨折影像学愈合时间为8~24周,平均(15.0±5.2)周,未见骨折不愈合。1例肱骨远端粉碎性骨折、1例胫腓骨远端粉碎性骨折伤口分别在术后7、10 d出现暗红色黏稠液体,后者后外侧伤口细菌培养为溶血性葡萄球菌。结论在创伤性骨折治疗中,医用硫酸钙降解速度较快,应用于表浅部位须谨慎。
[Abstract]:Objective to observe the early clinical and X-ray features of medical calcium sulfate in the treatment of traumatic fracture. Methods from September 2014 to January 2016, 23 cases of traumatic fracture were treated with medical calcium sulfate, 17 cases were male and 6 cases were female, the mean age was 41.6 years (20 years old). Immediately after operation, 1, 2, 4, 6, 8 weeks, 3, 6 months after operation, the degradation rate of medical calcium sulfate was calculated according to X-ray film. Results one week after operation, about 69% remained, 2 weeks, 53%, 4 weeks, 26%, 6 weeks, 7%, and 8 weeks, no clear findings were found. The initial onset time of callus was 3 ~ 9 weeks (mean 6.5 卤1.6 weeks), the healing time of fracture imaging was 8 weeks (24 weeks, mean (15.0 卤5.2) weeks), no nonunion was found in 1 case of comminuted fracture of distal humerus, 1 case of comminuted fracture of distal humerus was found. A case of comminuted fracture wound of distal tibia and fibula appeared dark red viscous fluid on the 7th and 10th day after operation respectively. The bacteria of the latter were cultured as Staphylococcus haemolyticus in posterolateral wound. Conclusion in the treatment of traumatic fracture, the degradation rate of medical calcium sulfate is faster, and the application of calcium sulfate in superficial area should be careful.
【作者单位】：天津医科大学研究生院;天津市天津医院;天津医科大学总医院;中国人民解放军464医院;
【基金】：科技部国家重点研发计划(编号:2016YFC0105805) 国家自然科学基金(编号:81572154)
【分类号】：R687.3

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