封闭负压引流技术联合抗生素骨水泥应用于下肢大面积撕脱伤的疗效

发布时间：2019-04-23 19:16

【摘要】：目的探讨抗生素骨水泥运用于下肢大面积皮肤撕脱伤创面的疗效。方法筛选该院2013年1月-2015年5月60例下肢大面积皮肤撕脱伤患者,分为研究组30例和对照组30例,对照组仅用封闭负压引流(VSD),研究采用VSD联合抗生素骨水泥,3~5d创面新鲜后将自体皮回植,观察记录两组术后皮片成活率、创面感染率和平均住院时间。结果研究组对照组相比,术后皮片成活率分别为(96.67±3.24)%和(73.33±4.86)%,差异有统计学意义(P=0.000);创面感染率分别为(3.33±1.35)%和(30.00±1.56)%,差异有统计学意义(P=0.000);平均住院时间分别为(10.44±2.53)和(20.81±7.42)d,差异有统计学意义(P=0.000)。结论抗生素骨水泥运用于下肢大面积皮肤撕脱伤能大大降低创面感染率,有效提高创面的植皮成活率,缩短患者住院时间,节约治疗费用,简便安全,值得推广。
[Abstract]:Objective to investigate the effect of antibiotic bone cement on large area skin avulsion wound of lower limbs. Methods from January 2013 to May 2015, 60 patients with large area skin avulsion of lower extremities were selected and divided into study group (n = 30) and control group (n = 30). In the control group, VSD combined with antibiotic bone cement was used in the (VSD), study of closed negative pressure drainage only. The survival rate of skin graft, the infection rate and the average hospitalization time of the skin graft were observed and recorded in the two groups after the wound was fresh for 5 days. Results compared with the control group, the survival rate of skin graft after operation was (96.67 卤3.24)% and (73.33 卤4.86)% respectively, the difference was statistically significant (P < 0.001). The infection rate of wound was (3.33 卤1.35)% and (30.00 卤1.56)% respectively (P < 0.001). The average hospitalization time was (10.44 卤2.53) days and (20.81 卤7.42) days, respectively, and the difference was statistically significant (P < 0.001). Conclusion the application of antibiotic bone cement in large area skin avulsion of lower extremities can greatly reduce the infection rate of wound, effectively improve the survival rate of skin graft, shorten the hospitalization time of patients, save the cost of treatment, be simple and safe, and be worth popularizing.
【作者单位】：广西壮族自治区柳州市人民医院创伤骨科;
【基金】：广西壮族自治区卫生厅自筹经费科研课题(No:Z2014429)
【分类号】：R658.3

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