去甲肾上腺素不同泵注速率对腰硬联合麻醉下剖宫产母婴的影响

发布时间：2019-06-13 23:17

【摘要】：目的探讨去甲肾上腺素(NE)不同泵注速率对腰硬联合麻醉下剖宫产母婴的影响。方法选择我院2016年10月至2017年9月收治的剖宫产产妇132例为研究对象,随机分为对照组、NE_1组、NE_2组和NE_3组,每组33例。对照组根据产妇实际情况,补救性单次注射NE。NE_1组、NE_2组和NE_3组均给予去甲肾上腺持续泵入,速率分别为0.03、0.04、0.05μg/(kg·min)。对比四组产妇低血压、高血压及恶心呕吐发生率,新生儿出生后1、5 min Apgar评分。结果与NE_1组、NE_2组和NE_3组比较,对照组产妇的低血压及恶心呕吐发生率明显更高(P0.05);与NE_1组和NE_2组比较,NE_3组产妇的低血压发生率明显更高(P0.05);NE_3组产妇高血压发生率高于对照组、NE_1组、NE_2组(P0.05)。四组新生儿出生后1、5 min Apgar评分比较,差异无统计学意义(P0.05)。结论在剖宫产腰硬联合麻醉中,NE持续泵入优于单次补救给药,对母婴影响较小,其中0.04μg/(kg·min)泵注速率较为理想。
[Abstract]:Objective to investigate the effect of different pumping rates of norepinephrine (NE) on cesarean section under combined spinal and epidural anesthesia. Methods from October 2016 to September 2017, 132 parturients undergoing cesarean section were randomly divided into control group (n = 33), NE_1 group (n = 33), NE_2 group (n = 33) and NE_3 group (n = 33). According to the actual situation of parturients, NE.NE_1 group, NE_2 group and NE_3 group were continuously injected with norepinephrine at a rate of 0.03, 0.04,0.05 渭 g / (kg 路min).), respectively. The incidence of hypotension, hypertension, nausea and vomiting in the four groups was compared, and the neonatal postbirth 1 and 5 min Apgar scores were compared. Results compared with NE_1 group, NE_2 group and NE_3 group, the incidence of hypotension and nausea and vomiting in control group was significantly higher than that in NE_1 group and NE_2 group (P 0.05). Compared with NE_1 group and NE_2 group, the incidence of hypotension in NE_3 group was significantly higher than that in control group, NE_1 group and NE_2 group (P 0.05). There was no significant difference in 5 min Apgar scores among the four groups (P 0.05). Conclusion continuous infusion of NE is superior to single remedial administration in cesarean section, and has little effect on mother and infant, and the pumping rate of 0.04 渭 g / (kg 路min) is ideal.
【作者单位】：西安医学院第二附属医院麻醉科
【分类号】：R614

【相似文献】