血清BALP、TRAP-5b及Singh指数预测老年髋部骨折发生的临床应用价值

发布时间：2019-07-24 09:57

【摘要】：目的探讨血清骨特异性碱性磷酸酶(BALP)、抗酒石酸酸性磷酸酶(TRAP-5b)及股骨近端骨小梁类型(Singh)指数在预测老年髋部骨折发生中的临床应用。方法老年髋部骨折患者50例为观察组,并选择同期体检的健康老年人45例为对照组。分析血清BALP、TRAP-5b及Singh指数的差异及采用Pearson相关性检验分析其相关性。结果观察组Singh指数主要集中于3~4级,对照组主要集中在4~5级,两组Singh指数分布的整体差异有统计学意义(P0.05)。观察组血清BALP、TRAP-5b水平均明显高于对照组,而Singh指数低于对照组(P0.05)。Pearson相关性分析显示,BALP与TRAP-5b呈正相关(r=0.476,P0.05),BALP和TRAP-5b与Singh指数均呈负相关(r=-0.571、-0.488,P0.05)。BALP、TRAP-5b和Singh指数预测髋部骨折发生的敏感度分别为72.37%、59.20%和64.00%,三者联合预测敏感度为93.50%。结论老年髋部骨折患者血清BALP、TRAP-5b水平升高,Singh指数降低,三者结合预测老年髋部骨折具有较高的敏感性,可作为老年髋部骨折风险预测的指标。
[Abstract]:Objective to investigate the clinical application of serum bone-specific alkaline phosphatase (BALP),) anti-tartrate acid phosphatase (TRAP-5b) and proximal femurs type (Singh) index in predicting the occurrence of hip fracture in the elderly. Methods 50 elderly patients with hip fracture were selected as observation group and 45 healthy elderly as control group. The difference of serum BALP,TRAP-5b and Singh index was analyzed and the correlation was analyzed by Pearson correlation test. Results the Singh index was mainly concentrated in 3 鈮，

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