miR-199在退变椎间盘髓核细胞中的表达及作用调控机制研究
【文章页数】:120 页
【学位级别】:博士
【部分图文】:
图1高通量分析检测差异性表达的miRNAsFig.1StatisticalscreeningofdifferentiallyexpressedmiRNAsindegeneratedintervertebraldiscNPtissue
图1高通量分析检测差异性表达的miRNAs1StatisticalscreeningofdifferentiallyexpressedmiRNAsindegeneintervertebraldiscNPtissue2.退变椎间盘NP组织较正常椎间....
图3退变和正常椎间盘组织中TNF-α的表达量Fig.3TheexpressionlevelofTNF-αindegenerativeNPtissueandnormal
图2退变和正常椎间盘NP组织中miR-199的表达水平TheexpressionofmiR-199indegenerativediscNPtissueanintervertebraldiscNPtissue(*P<0.05vs.norm....
图1TNF-α刺激0-48h人NP细胞活性变化
图1TNF-α刺激0-48h人NP细胞活性变化。Fig.1Thecellviabilityofhumannucleuspulposuscellsduring0-4underTNF-αtreatment(*P<0.05vs.control....
图2TNF-α刺激0-48h人NP细胞LDH活性变化
图2TNF-α刺激0-48h人NP细胞LDH活性变化ig.2TheLDHviabilityofhumannucleuspulposuscellsduring0-48hunTNF-αtreatment(*P<0.05vs.contro....
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