白内障术后应用非甾体类滴眼液对黄斑水肿的预防作用探讨

发布时间：2018-09-02 07:45

【摘要】：目的研究非甾体类滴眼液对白内障患者术后发生黄斑囊样水肿(CME)几率的影响。方法分析2012年7月至2014年6月在本院接受治疗的白内障患者的临床资料。根据患者的治疗方案随机将患者分为A组(术前3d使用普拉洛芬滴眼液)、B组(术后使用普拉洛芬滴眼液)、C组(术前、术后不采用任何NASIDs)。比较三组患者的术后不同时间点CME的发生率。结果本研究共入组患者92例(92眼),其中A组32例(32眼),B组29例(29眼),C组31例(31眼)。在术后1 d、1 w、2 w、4 w时,三组患者的黄斑水肿发生率组间比较无显著性差异(P0.05),而在术后6 w时,三组患者组间比较具有统计学差异(P0.05),且C组患者的发生率显著高于其他两组;术后12 w时,三组患者黄斑水肿发生率组间比较有统计学差异(P0.05),且B、C组患者的发生率显著高于A组。结论术前开始使用非甾体类滴眼液较术后使用可显著降低白内障患者术后CME的发生率。
[Abstract]:Objective to study the effect of non-steroidal eye drops on (CME) probability of macular cystic edema after cataract surgery. Methods the clinical data of cataract patients treated in our hospital from July 2012 to June 2014 were analyzed. Patients were randomly divided into group A (Praprofen eye drops 3 days before operation) group B (using Praprofen eye drops after operation) and group C (no NASIDs). Before and after operation). The incidence of CME at different time points after operation was compared among the three groups. Results there were 92 patients (92 eyes) in this study, including 32 cases (32 eyes) in group A, 29 cases (29 eyes) in group B, 31 cases (31 eyes) in group C. There was no significant difference in the incidence of macular edema between the three groups at 1 and 2 weeks after operation (P0.05), but at 6 weeks after operation, there was statistical difference among the three groups (P0.05), and the incidence of macular edema in group C was significantly higher than that in the other two groups. At 12 weeks after operation, the incidence of macular edema in the three groups was significantly higher than that in group A (P0.05), and the incidence of macular edema in group B was significantly higher than that in group A. Conclusion NSAID can significantly reduce the incidence of postoperative CME in cataract patients.
【作者单位】：河南省信阳市中心医院眼科;
【分类号】：R779.6

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