支撑喉窥镜下切除声带良性增生性病变的疗效及复发率观察

发布时间：2018-12-07 09:07

【摘要】：目的 :分析支撑喉窥镜下切除声带良性增生性病变的临床效果及对患者复发率的影响,探讨其临床应用价值。方法 :将我院2013年3月—2015年3月收治的138例声带良性增生性病变患者作为观察组,并选取同期30名健康体检者,作为对照组,检测对照组入组时及观察组治疗前后声学参数变化,分析该方案的疗效,并实施为期1年随访,记录观察组患者复发情况。结果 :所有患者均顺利完成手术,未见术后并发症发生。观察组术前声学参数均高于对照组,其术后1周时基频微扰、振幅微扰、标准化噪能量较术前降低,差异有统计学意义(P0.05),患者术后2周时声学参数与对照组入组时比较,差异无统计学意义(P0.05)。术后6个月时,治愈124例,好转9,无效5例,总有效率为96.38%;术后1年内,138例患者中复发2例,复发率为1.45%。结论 :支撑喉窥镜下切除声带良性增生性病变可早期改善患者声学参数,具有良好的临床疗效与安全性,且可将患者复发率控制在较低水平。
[Abstract]:Objective: to analyze the clinical effect of laryngoscopic resection of benign proliferative lesions of vocal cord and its influence on the recurrence rate of patients, and to explore its clinical application value. Methods: 138 patients with benign proliferative lesions of vocal cord were treated in our hospital from March 2013 to March 2015 as observation group, and 30 healthy persons were selected as control group. The changes of acoustic parameters in the control group and before and after treatment were detected and the curative effect was analyzed. The patients in the observation group were followed up for one year to record the recurrence of the patients in the observation group. Results: all patients successfully completed the operation, no postoperative complications occurred. The preoperative acoustic parameters in the observation group were higher than those in the control group, and the fundamental frequency perturbation, amplitude perturbation and standardized noise energy were decreased 1 week after operation (P0.05). There was no significant difference in acoustic parameters between the patients and the control group 2 weeks after operation (P0.05). At 6 months after operation, 124 cases were cured, 9 cases were improved, 5 cases were ineffective, the total effective rate was 96.38%, within 1 year after operation, there were 2 cases of recurrence in 138 cases, and the recurrence rate was 1.45%. Conclusion: resection of benign proliferative lesions of vocal cord under laryngoscope can improve the acoustic parameters of patients early, have good clinical efficacy and safety, and can control the recurrence rate of patients at a lower level.
【作者单位】：扬州友好医院耳鼻喉科;南京医科大学附属无锡人民医院耳鼻喉科;
【分类号】：R767.91

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