高尿酸血症对急性心肌梗死患者预后的影响

发布时间：2018-01-31 05:35

本文关键词： 冠心病急性心肌梗死高尿酸血症预后　出处：《新疆医科大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:研究高尿酸血症对急性心肌梗死(AMI)预后的影响。方法:对连续收集的新疆医科大学第二附属医院住院的122例AMI患者根据血尿酸水平分为两组:正常血尿酸组(91)和高尿酸血症组(31),分析两组的临床特征及基线水平,比较影像学结果,再入院率,再发不良心血管事件以及死亡率的不同,以探讨高尿酸血症对急性心肌梗死预后的影响。结果:1、高尿酸血症组无论是合并陈旧性心梗的比例,还是合并高血压的比例,均显著高于正常血尿酸组(P0.05)。在心功能分级上,高尿酸血症组明显高于正常血尿酸组(P0.05)。2、高尿酸血症组室壁节段运动异常比例高于正常血尿酸组(P0.05),高尿酸血症组在左室收缩末径以及左室舒张末径均大于正常血尿酸组(P0.05)。患者冠脉狭窄程度无明显统计学差异(P0.05),高尿酸血症组多支病变比例高于正常血尿酸组(P0.05)。3、半年内再入院和再发心血管不良事件和正常血尿酸组相比无明显统计学差异(P0.05)。但是,高尿酸血症患者半年内死亡率较高(P0.05)。结论:高尿酸血症与AMI的不良预后有一定关系。
[Abstract]:Objective: to study the effect of hyperuricemia on acute myocardial infarction (AMI). Methods: one hundred and twenty-two consecutive AMI patients in the second affiliated Hospital of Xinjiang Medical University were divided into two groups according to the level of uric acid: normal uric acid group (91) and hyperuricemia group (1). 31). The clinical characteristics and baseline level of the two groups were analyzed, and the differences of imaging results, readmission rate, recurrent adverse cardiovascular events and mortality were compared. To investigate the effect of hyperuricemia on the prognosis of acute myocardial infarction. In cardiac function grade, hyperuricemia group was significantly higher than normal blood uric acid group (P 0.05). The abnormal rate of ventricular wall motion in hyperuricemia group was higher than that in normal blood uric acid group (P0.05). The left ventricular end-systolic diameter and left ventricular end-diastolic diameter in hyperuricemia group were higher than those in normal blood uric acid group (P 0.05). The proportion of multivessel lesions in hyperuricemia group was higher than that in normal blood uric acid group (P0.050.3.). There was no significant difference between readmission and recurrent cardiovascular adverse events in half a year compared with normal uric acid group (P 0.05). The mortality of patients with hyperuricemia within half a year was higher than that of P0.050.Conclusion: hyperuricemia is related to the poor prognosis of AMI.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R589.7;R542.22

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