基线血压对肾动脉去交感神经术降压效果的影响

发布时间：2018-02-10 10:27

  本文关键词： 基线因素 顽固性高血压 肾动脉去交感神经术 动态血压　出处：《临床心血管病杂志》2017年01期 　论文类型：期刊论文

【摘要】：目的:分析顽固性高血压患者基线因素对肾动脉去交感神经术(RDN)降压疗效的影响,为RDN临床病患的入选提供初步指导。方法:回顾性分析2013-2015年于普陀医院心内科行RDN治疗的23例顽固性高血压患者记录数据,采用单因素筛选和多因素分析得出RDN降压效果的主要影响因素。结果:术前24h平均收缩压水平是影响RDN降压效果的最重要因素。无论低压组(ABPSYS≤150mmHg)还是高压组(ABPSYS150mmHg)经过RDN术后半年的24h平均收缩压血压都维持在140mmHg左右。低压组患者,术后6个月平均血压减少(8.3±5.7)/(4.6±3.2)mmHg(P0.05),RDN有效率(术后6个月收缩压值下降大于或等于10mmHg)为62.5%;高压组降压(28.9±12.1)/(12.4±7.4)mmHg(与术前比较P0.05),RDN有效率高达93.3%。结论:基线血压显著影响RDN降压效果,且ABPSYS150mmHg患者RDN术降压效果更明显。根据动态血压基线值选择合适的患者,RDN术可以使患者更能获益。
[Abstract]:Objective: to analyze the effect of baseline factors on the antihypertensive effect of RDN in patients with refractory hypertension. Methods: the data of 23 patients with refractory hypertension treated with RDN in Cardiology Department of Putuo Hospital from 2013 to 2015 were analyzed retrospectively. Univariate screening and multivariate analysis were used to find out the main influencing factors of RDN hypotensive effect. Results: the mean systolic blood pressure (SBP) level at 24 hours before operation was the most important factor affecting the antihypertensive effect of RDN, whether in low pressure group (ABPSYS 鈮，

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