慢性充血性心力衰竭患者左室射血分数与心脏变时不良的相关性

发布时间：2018-02-24 03:49

本文关键词： 慢性充血性心力衰竭左室射血分数心脏变时功能不良心脏变时性指数运动试验 CV事件　出处：《广东医学》2017年S1期 　论文类型：期刊论文

【摘要】：目的探索慢性充血性心力衰竭(CHF)患者左室射血分数(EF)与心脏变时功能不良的相关性。方法入选CHF患者180例,根据其EF值分为3组,A组60例(EF值范围:30%~35%),B组61例(EF值范围:36%~40%),C组59例(EF值范围:41%~45%),入选时患者常规检测心脏彩超,如有心肌梗死或脑卒中病史的患者,常规检测心脏CT或脑部CT。入选后随访12个月,分别在入组后5 d内、第6个月末、第12个月末对患者行运动试验(患者配戴动态心电图仪,在平直走廊尽可能快地步行3 min),然后测定心脏变时性指数(CRI),记录随访期心血管不良事件发生情况。结果 A、B、C三组在入组后5 d内的CRI值分别为0.62±0.14、0.66±0.18、0.70±0.16,组间差异无统计学意义(P0.05);第6个月末分别为0.66±0.15、0.70±0.19、0.77±0.24,A组与C组差异有统计学意义(P0.05),B组与A、C组差异无统计学意义(P0.05);第12个月末分别为0.69±0.26、0.76±0.21、0.86±0.20,组间差异有统计学意义(P0.05);随访期心血管不良事件发生率分别为15.0%、8.2%、6.8%,A组与B、C两组差异有统计学意义(P0.05),B组与C组差异无统计学意义(P0.05)。结论在CHF患者中,EF值与心脏变时功能不良呈负相关,在CHF患者完善CRI检测,有利于预测患者预后,及早治疗,降低患者风险。
[Abstract]:Objective to investigate the relationship between left ventricular ejection fraction (EFF) and chronotropic dysfunction in patients with chronic congestive heart failure (CHF). According to their EF values, they were divided into three groups: group A, 60 cases with EF value range 30: 30, and group B, 61 cases with EF range of 61 cases with EF value of: 36, 40, 40, group C, 59 cases with EF value in the range of: 41and 4545. The patients were routinely examined with echocardiography, if they had a history of myocardial infarction or cerebral apoplexy. The patients were followed up for 12 months after routine detection of cardiac CT or brain CT. Exercise tests were performed on the patients within 5 days, 6 months, 12 months after admission (patients wore dynamic electrocardiograph). Walk 3 mins as fast as possible in the flat and straight corridor, then measure the cardiac chronotropic index (CRI) and record the occurrence of cardiovascular adverse events during the follow-up period. Results the CRI values of the three groups were 0.62 卤0.140.66 卤0.180.70 卤0.16 within 5 days after entering the group respectively. There was no statistical difference between the three groups. There was no significant difference between group A and group C at the end of the sixth month (P 0.05) and 0.69 卤0.260.76 卤0.21 卤0.86 卤0.20 at the end of 12 months, and there was significant difference between group A and C in the occurrence of cardiovascular adverse events during follow-up period (P 0.05), and the difference between group A and group C was statistically significant (P 0.05) at the end of the sixth month, and there was no significant difference between group A and group C at the end of the sixth month (P 0.05), and the difference was 0.69 卤0.260.76 卤0.21 卤0.86 卤0.20 at the end of 12 months, and there was significant difference between the two groups in the occurrence of cardiovascular adverse events in the follow-up period. There was significant difference between group A and group B (P 0.05) and group C (P 0.05). Conclusion there is a negative correlation between EF and cardiac dysfunction in patients with CHF. Improving CRI detection in patients with CHF is helpful to predict prognosis, early treatment and reduce the risk of patients.
【作者单位】：茂名市中医院特诊病区;
【分类号】：R541.61

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