成人房颤急性脑梗死与非房颤急性脑梗死住院患者肾功能不全的对照分析

发布时间：2018-03-05 12:46

本文选题：急性脑梗死　切入点：房颤　出处：《实用医学杂志》2017年07期 　论文类型：期刊论文

【摘要】：目的:比较成人心房纤颤(AF)是否比非AF急性脑梗死住院患者有较高的肾功能不全发生率,并分析可能的危险因素。方法:以本院神经内科住院的374例AF急性脑梗死患者为研究对象(AF组),随机选取同期500例非AF急性脑梗死的患者作为对照组,对比两组肾功能不全[肾小球滤过率(e GFR)60 m L/(min·1.73 m2)]是否有差异,采用非条件Logistic回归分析AF组肾功能不全的危险因素。结果:AF组374例,肾功能不全114例(30.5%);非AF组500例,肾功能不全75例(15.0%),组间差异有统计学意义(P=0.000),比值比(OR)为2.485,AF组与非AF组的e GFR分别为(77.75±39.89)m L/(min·1.73 m2)和(96.93±39.14)m L/(min·1.73 m2)。回归分析发现AF组中导致肾功能不全的危险因素有心功能不全(OR=2.057)、高血压病(OR=1.826)、糖尿病(OR=1.897)、高尿酸血症(OR=3.161)。结论:成年AF急性脑梗死患者有肾功能不全者明显高于非AF急性脑梗死者,该组患者导致肾功能不全的危险因素有心功能不全、高血压病、糖尿病、高尿酸血症。
[Abstract]:Objective: to compare the incidence of renal insufficiency in adult patients with atrial fibrillation (AF) compared with non-AF patients with acute cerebral infarction. Methods: a total of 374 patients with AF acute cerebral infarction (ACI) in neurology department of our hospital were randomly selected as control group and 500 patients with non-AF acute cerebral infarction (ACI) in the same period were randomly selected as control group. The risk factors of renal insufficiency in AF group were analyzed by non conditional Logistic regression analysis. Results there were 374 cases in group AF, 114 cases with renal insufficiency, 30.5% with renal insufficiency, 500 cases with non AF, and 3 cases with renal failure with different renal function (glomerular filtration rate, glomerular filtration rate = 1.73 m ~ (2), n = 374), no AF group (n = 500), and no AF group (n = #number0#), and no AF group (n = #number0#). There were significant differences between the two groups (P < 0.000). The e GFR of AF group and non-AF group were 77.75 卤39.89 mL / min 路1.73 m2 and 96.93 卤39.14 mL / min 路1.73 m2, respectively. Regression analysis showed that the risk factors of renal insufficiency in AF group were incomplete cardiac function. Conclusion: the patients with acute cerebral infarction with AF have higher renal function than those with acute cerebral infarction without AF, and the patients with acute cerebral infarction with hyperuricemia have higher renal function than those with acute cerebral infarction of non-AF, the patients with acute cerebral infarction have higher renal function than those with non-AF acute cerebral infarction, and the patients with hyperuricemia and hyperuricemia are 1.826, 1.826, 1.826 and 1.826, respectively. Risk factors for renal insufficiency in this group were cardiac dysfunction, hypertension, diabetes, and hyperuricemia.
【作者单位】：广东医科大学附属惠州医院广东省惠州市中心人民医院;
【分类号】：R541.75;R743.33

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