朝鲜族和汉族女性正常范围内GGT与高血压的相关性研究

发布时间：2018-03-29 06:14

本文选题：谷氨酰基转肽酶　切入点：高血压　出处：《中国卫生统计》2017年05期

【摘要】：目的探讨朝鲜族和汉族女性的正常范围内谷氨酰基转移酶(GGT)与高血压的相关性。方法选取2011年5月-2012年2月参加健康体检的20岁以上成年女性3341名,测定身高、体重、血压、血脂、血糖、肝功等指标,分析GGT与各项指标的相关性及不同GGT水平的高血压的患病风险。结果朝鲜族和汉族女性GGT水平与BMI、SBP、DBP、TC、TG、FPG、UA均呈正相关,朝鲜族和汉族女性未调整时GGT上四分位组高血压患病危险分别是下四分位组的2.844倍(95%CI:2.006～4.033)和4.992倍(95%CI:3.280～7.599),调整年龄、BMI、TC、TG、FPG、UA和GFR等因素后上四分位组高血压患病危险是下四分位组的1.811倍(95%CI:1.230～2.666)和2.115倍(95%CI:1.301～3.440);并且不同模型中朝鲜族和汉族女性均随着GGT水平的增加,患高血压的危险增加。结论正常范围内GGT水平的升高可以预测高血压的发生,并且对于汉族女性的预测作用强于朝鲜族。
[Abstract]:Objective to investigate the correlation between GGTs and hypertension in normal range of Korean and Han women. Methods 3341 adult women over 20 years old who took part in health examination from May 2011 to February 2012 were selected and their height, weight and blood pressure were measured. Blood lipids, blood glucose, liver function, and so on. The correlation between GGT and the indexes and the risk of hypertension with different GGT levels were analyzed. The risk of hypertension in the upper quartile GGT group was 2.844 times higher than that in the lower quartile group when the Korean and Han nationality women were not adjusted. The risk of hypertension in the upper quartile group was lower than that in the lower quartile group, respectively. The risk of hypertension in the upper quartile group was lower than that in the lower quartile group after adjusting for the factors such as CI: 3.280 and 7.5990.After adjusting for age, the risk of hypertension in the upper quartile group was lower than that in the lower quartile group. And 2.115 times as much as 95: 1.301 and 3.440; and all the Korean and Han women in different models increased with the level of GGT. Conclusion the increase of GGT level in normal range can predict the occurrence of hypertension, and the predictive effect on Han women is stronger than that of Korean nationality.
【作者单位】：延边大学;延边大学医学院流行病学与统计学教研室;
【基金】：国家自然基金资助(81660562) 吉林省科技厅项目(201015248) 延边大学创新课题(ydbksky2016176)
【分类号】：R544.1

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