芪参益气滴丸治疗慢性心力衰竭对容量负荷及疗效的影响

发布时间：2018-04-12 07:16

本文选题：芪参益气滴丸 + 慢性心力衰竭　；参考：《中药药理与临床》2017年05期

【摘要】：目的:分析芪参益气滴丸治疗慢性心力衰竭对容量负荷及疗效的影响。方法:受试对象为2016年1月~2016年6月在我院就诊的140例慢性心力衰竭患者,所有患者均进行常规方案诊治,观察组另服用芪参益气滴丸,对比该药对相关指标的影响。结果:观察组疗效明显高于对照组(91.43%比74.29%)。治疗后,观察组6MWT、症候得分、MLHFFQ得分分别为(364.8±20.5)m、(4.16±0.69)分、(26.59±4.75)分,均明显优于对照组(329.8±17.2)m、(5.31±0.74)分、(35.11±5.08)分。治疗后,观察组LVEDD、LVESD、LVEF、SV分别为(52.13±3.05)mm、(42.09±3.04)mm、(53.67±4.45)%、(58.94±3.88)ml/min,均明显优于对照组(56.27±3.12)mm、(45.16±3.51)mm、(48.93±4.31)%、(54.85±3.73)ml/min。治疗后,观察组BNP、TNF-ɑ、IL-6水平分别为(314.6±38.9)pg/ml、(22.15±4.49)ng/L、(118.4±15.9)ng/L,均明显低于对照组(394.8±41.5)pg/ml、(29.83±4.88)ng/L、(152.1±17.6)ng/L。治疗后,观察组ECW/TBW、ECW/ICW分别为(0.384±0.041)、(0.451±0.055),均明显优于对照组(0.397±0.063)、(0.442±0.062)。结论:常规治疗上加用芪参益气滴丸,可提高慢性心力衰竭治疗疗效,改善心功能和容量负荷。
[Abstract]:Objective: to analyze the effect of Qishen Yiqi dropping pill on volume load and effect of chronic heart failure.Methods: 140 patients with chronic heart failure were treated in our hospital from January 2016 to June 2016. All the patients were treated with routine regimen. The observation group took Qishen Yiqi dropping pills separately.Results: the curative effect of the observation group was significantly higher than that of the control group (91.43% vs 74.29%).After treatment, the symptom score and MLHFFQ score of the observation group were 364.8 卤20.5mFQ (4.16 卤0.69) and 26.59 卤4.75, respectively, which were significantly better than those of the control group (329.8 卤17.2mng, 5.31 卤0.74) and 35.11 卤5.08, respectively.After treatment, the levels of BNP-TNF- 伪 IL-6 in the observation group were 314.6 卤38.9 ng / ml and 22.15 卤4.49 ng / L respectively, which were significantly lower than those in the control group (394.8 卤41.5 ng / ml, 29.83 卤4.88 ng / L, 152.1 卤17.6ngL / L, respectively).After treatment, the ECW / TBWV / ICW ratio in the observation group was 0.384 卤0.041 卤0.055, respectively, which was significantly higher than that in the control group (0.397 卤0.063).Conclusion: the routine therapy with Qishen Yiqi dropping pill can improve the curative effect of chronic heart failure and improve cardiac function and volume load.
【作者单位】：湖南省人民医院心内科;湘雅医学院附属三医院药剂科;
【基金】：湖南省人民医院仁术基金(2008-16):前列腺素E1对PCI木后患者心血管事件的影响及其机理研究
【分类号】：R541.6

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