人参芍药散加味联合运动康复治疗冠心病稳定性心绞痛的临床疗效观察

发布时间：2018-04-13 20:20

本文选题：人参芍药散 + 稳定性心绞痛　；参考：《黑龙江中医药大学》2017年硕士论文

【摘要】：目的:观察人参芍药散加味联合运动康复对气虚血瘀型冠心病稳定性心绞痛患者的临床症状、运动耐量及生活质量的影响。方法:选用随机数字表将90例冠心病稳定性心绞痛患者分三组,对照组A组,治疗组B组和C组,各组为30例。对照组A组予以西药常规治疗,治疗组B组在A组的基础上加人参芍药散加味,治疗组C组在B组的基础上联合运动康复,疗程4周。观察治疗前后三组患者心绞痛疗效,中医症状,6分钟步行试验及西雅图心绞痛量表的变化。三组患者治疗前后的数据采用spss20.0进行统计分析。结果:1.治疗后三组患者的心绞痛症状积分、中医证候积分较治疗前有改善,经单因素方差分析比较,p0.05,差异有统计学意义。组间两两对比,C组与B组对比,差异无统计学意义(p0.05);C组与A组、B组与A组对比差异均有统计学意义(p0.05)。2.治疗后三组患者心电图总有效率经秩和检验比较,p0.05,差异无统计学意义。3.治疗后三组患者的心绞痛有效率、中医症候有效率较治疗前有改善,经秩和检验比较,p0.05,差异有统计学意义。组间两两对比,C组与B组比较,差异无统计学意义(p0.0167);C组与A组、B组与A组对比差异均有统计学意义(p0.0167)。4.治疗后三组患者的西雅图量表积分在躯体活动受限程度、心绞痛稳定状态、心绞痛发作情况、治疗满意程度评分、疾病认识程度方面较治疗前有改善,经单因素方差分析比较,p0.05,差异有统计学意义。组间两两对比,C组与B组对比,差异无统计学意义(p0.05);C组与A组、B组与A组对比差异均有统计学意义(p0.05)。5.治疗后三组患者的6分钟步行距离较治疗前均有提高,经单因素方差分析比较,p0.05,差异有统计学意义。组间两两对比,C组与B组、C组与A组、B组与A组对比差异均有统计学意义(p0.05)。结论:1.人参芍药散加味可以改善稳定性心绞痛患者的心绞痛症状及生活质量。2.人参芍药散加味能够改善稳定性心绞痛患者的中医证候。3.人参芍药散加味联合运动康复在改善稳定性心绞痛患者的临床症状及生活质量,同时可以明显增加患者的运动耐量。
[Abstract]:Objective: to observe the clinical symptoms, exercise tolerance and quality of life of patients with stable angina pectoris of coronary heart disease with Qi deficiency and blood stasis.Methods: 90 patients with stable angina pectoris of coronary heart disease were randomly divided into three groups: control group A, treatment group B and group C, 30 cases in each group.The control group A was treated with routine western medicine, the treatment group B was treated with Ginseng Shaoyao Powder on the basis of group A, and the treatment group C combined with exercise rehabilitation on the basis of group B. the course of treatment was 4 weeks.The effect of angina pectoris before and after treatment, 6 minute walking test of TCM symptoms and changes of Seattle angina scale were observed.The data before and after treatment were analyzed by spss20.0.The result is 1: 1.After treatment, the symptom score of angina pectoris and the score of TCM syndrome in three groups were improved compared with those before treatment, and the difference was statistically significant by single factor analysis of variance (ANOVA).There was no significant difference between group C and group B, there was no significant difference between group C and group A, and there was significant difference between group B and group A.After treatment, the total effective rate of electrocardiogram in the three groups was compared by rank sum test (P 0.05), and the difference was not statistically significant. 3.After treatment, the effective rate of angina pectoris and the effective rate of TCM symptom were improved in the three groups, and the difference was statistically significant by rank sum test (P 0.05).There was no significant difference between C group and B group. There was no significant difference between C group and A group.After treatment, the Seattle scale scores of the three groups were improved in terms of the degree of restricted physical activity, stable state of angina pectoris, angina pectoris attack, treatment satisfaction score, and disease awareness.The difference was statistically significant by single factor analysis of variance (P 0.05).There was no significant difference between group C and group B, there was no significant difference between group C and group A, and there was significant difference between group B and group A.After treatment, the 6-minute walking distance of the three groups was significantly higher than that before treatment, and the difference was statistically significant by univariate analysis of variance (P 0.05).There were significant differences between C group and B group, C group, A group and A group (P 0.05).Conclusion 1.Ginseng Shaoyao Powder can improve angina symptoms and quality of life of patients with stable angina pectoris.Ginseng Shaoyao Powder can improve the Chinese medicine syndrome of stable angina pectoris. 3.Ginseng Shaoyao Powder combined with exercise rehabilitation can improve the clinical symptoms and quality of life of patients with stable angina pectoris at the same time can significantly increase the exercise tolerance of patients.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R541.4

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