老年非杓型高血压患者血钾水平与血压水平及继发缺血性脑卒中的关系

发布时间：2018-04-14 19:14

本文选题：低血钾 + 非杓型高血压　；参考：《山东医药》2017年33期

【摘要】：目的探讨老年非杓型高血压患者血钾水平与血压及继发缺血性脑卒中风险的相关性。方法选取110例老年非杓型高血压患者,根据血清血钾水平将患者分为正常血钾组(53例)和低血钾组(58例)。通过Pearson相关分析评价血钾与患者的血压水平、颈部动脉内膜-中膜厚度(IMT)的相关性,利用Logistic回归筛选缺血性脑卒中的高危因素。结果低血钾组重度高血压、中度高血压以及颈动脉重度狭窄、中度狭窄患者比例高于正常血钾组(P均0.05);低血钾组24 h平均收缩压、24 h平均舒张压、夜平均收缩压、夜平均舒张压均高于正常血钾组(P均0.05);低血钾组IMT大于正常血钾组(P0.05)。Pearson相关分析显示低血钾患者血钾水平与血压、IMT呈负相关(P均0.05),Logistic回归分析结果表明血钾水平是仅次于IMT的影响脑卒中发生的高危因素。结论低血钾可使老年非杓型高血压患者的血压水平升高,且易诱发缺血性脑卒。
[Abstract]:Objective to investigate the correlation between serum potassium level and blood pressure and risk of secondary ischemic stroke in elderly patients with non-dipper hypertension.Methods 110 elderly patients with non-dipper hypertension were divided into normal group (53 cases) and hypokalemia group (58 cases) according to serum potassium level.The correlation between blood potassium and blood pressure and carotid intima-media thickness (IMT) was evaluated by Pearson correlation analysis. Logistic regression was used to screen the risk factors for ischemic stroke.Results the proportion of patients with severe hypertension, moderate hypertension and severe stenosis of carotid artery in hypokalemia group was higher than that in normal blood potassium group (P 0.05), the mean systolic blood pressure in hypokalemia group was 24 h mean diastolic blood pressure (DBP) and night mean systolic blood pressure (SBP).The IMT of hypokalemia group was higher than that of normal kalium group (P < 0.05). Pearson correlation analysis showed that there was a negative correlation between blood potassium level and blood pressure in hypokalemic patients. Logistic regression analysis showed that serum potassium level was only lower in hypokalemia group than that in normal blood potassium group (P < 0.05).The risk factors affecting stroke are inferior to IMT.Conclusion hypokalemia can elevate blood pressure and induce ischemic stroke in elderly patients with non-dipper hypertension.
【作者单位】：重庆市第十三人民医院;
【基金】：重庆卫计委资助项目(2015MSXM084)
【分类号】：R544.1

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