CT评价主动脉弹性与冠状动脉钙化的相关性

发布时间：2018-04-21 09:47

本文选题：体层摄影术 + X线计算机　；参考：《中国医学影像技术》2017年06期

【摘要】：目的采用CT探讨主动脉弹性与冠状动脉钙化的相关性。方法搜集我院拟诊为冠心病并接受冠状动脉CTA检查病例,将图像质量能满足主动脉弹性测量的111例患者纳为研究对象,分为钙化阴性组(n=43)和钙化阳性组(n=68),根据钙化积分值将钙化阳性组分为轻度、中度、重度钙化3组。将原始数据每隔5%R-R间期进行全时相自动离线重建,测量各R-R间期主动脉横截面积及直径,计算评价主动脉弹性的4个参考指标:直径变化率(%A0)、动脉可扩张度(A0D)、动脉顺应性(A0C)及动脉僵硬度(A0SI)。分析主动脉弹性与冠状动脉钙化的关系。结果钙化阳性组的%A0、A0D、A0C小于钙化阴性组,而A0SI大于钙化阴性组(P均0.05)。钙化阳性组中轻度、中度、重度钙化3组间主动脉弹性差异无统计学意义(P均0.05)。冠状动脉钙化积分与%A0、A0D、A0C呈负相关,与A0SI呈正相关。结论主动脉弹性与冠状动脉钙化积分有相关性,两者联合应用可以为早期诊断冠心病提供依据。
[Abstract]:Objective to investigate the correlation between aortic elasticity and coronary artery calcification by CT. Methods A total of 111 patients with coronary artery disease (CHD) and coronary artery CTA (CTA) were studied. The calcification positive group was divided into 3 groups according to the calcification integral value: mild, moderate and severe calcification. The original data were reconstructed off-line automatically every 5%R-R interval, and the cross-sectional area and diameter of aorta were measured in each R-R interval. Four reference indexes for evaluating aortic elasticity were calculated: the rate of change in diameter, the degree of dilatability of the artery, the compliance of the artery, and the stiffness of the artery, and the stiffness of the artery. To analyze the relationship between aortic elasticity and coronary artery calcification. Results the positive calcification group was smaller than the calcified negative group, and the A0SI was higher than that in the calcified negative group (P < 0.05). There was no significant difference in aortic elasticity among mild, moderate and severe calcification groups (P < 0.05). The coronary artery calcification score was negatively correlated with A 0 D, A 0 C, and positively correlated with A0SI. Conclusion there is a correlation between aortic elasticity and coronary artery calcification score, and the combination of them can provide evidence for early diagnosis of coronary heart disease.
【作者单位】：华北理工大学附属医院CT室;华北理工大学研究生学院;华北理工大学附属医院核医学科;华北理工大学附属医院放射科;
【分类号】：R541.4;R816.2

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