老年急性非ST段抬高型心肌梗死患者心血管不良事件的发生及影响因素

发布时间：2018-05-01 00:33

本文选题：急性非ST段抬高型心肌梗死 + 心血管不良事件　；参考：《中国老年学杂志》2017年12期

【摘要】：目的探讨老年急性非ST段抬高型心肌梗死患者心血管不良事件的发生及影响因素。方法选择300例60岁及以上急性非ST段抬高型心肌梗死患者作为老年组,300例60岁以下急性非ST段抬高型心肌梗死患者作为非老年组。收集两组患者的临床资料及心血管不良事件的发生情况。结果老年组院内及3年内再发心绞痛、再发心肌梗死、心力衰竭、死亡的发生率均高于非老年组(P0.05)。单因素分析显示:高血压史、糖尿病史、阿司匹林应用、血小板分布宽度、低密度脂蛋白(LDL)与老年心肌梗死患者3年内心血管不良事件的发生有关(P0.05),性别、吸烟史、他汀类应用、氯吡格雷应用、血小板计数、高密度脂蛋白(HDL)、总胆固醇(TC)和甘油三酯(TG)水平与老年心肌梗死患者3年内心血管不良事件的发生无关(P0.05)。多因素分析显示:出院后规律服用阿司匹林为老年心肌梗死患者3年内心血管不良事件独立保护因素(P0.05),高血小板分布宽度和LDL是老年心肌梗死患者3年内心血管不良事件独立危险因素(P0.05)。结论急性非ST段抬高型心肌梗死患者心血管不良事件的发生率高,出院后规律服用阿司匹林可预防3年内心血管不良事件的发生,高水平血小板分布宽度和LDL可增加3年内心血管不良事件发生。
[Abstract]:Objective to investigate the incidence and influencing factors of cardiovascular adverse events in elderly patients with acute non ST segment elevation myocardial infarction. Methods 300 patients aged 60 and above with acute non ST segment elevation myocardial infarction were used as the elderly group and 300 patients with acute non ST segment elevation myocardial infarction under 60 years of age as non elderly group. The clinical effects of two groups of patients were collected. Results the incidence of recurrent angina, recurrent myocardial infarction, heart failure and death in the elderly group was higher than that in the non elderly group (P0.05). Single factor analysis showed that the history of hypertension, diabetes, aspirin, platelet distribution, low density lipoprotein (LDL) and old myocardium The incidence of 3 years of inwardly adverse events in the patients (P0.05), sex, smoking history, statins, clopidogrel, platelet count, high density lipoprotein (HDL), total cholesterol (TC) and triglyceride (TG) levels were not related to the occurrence of 3 years of cardiovascular adverse events in elderly patients with myocardial infarction (P0.05). Multivariate analysis showed: Aspirin as an independent protective factor (P0.05) for 3 year innermost vascular adverse events in elderly patients with myocardial infarction (P0.05), high platelet distribution width and LDL are independent risk factors (P0.05) for 3 year innermost vascular adverse events in elderly patients with myocardial infarction (P0.05). Conclusion the incidence of adverse cardiovascular events in patients with acute non ST segment elevation myocardial infarction High rate, aspirin after discharge can prevent 3 years of cardiovascular adverse events. The high level of platelet distribution and LDL can increase the incidence of cardiovascular adverse events in 3 years.

【作者单位】：宁波市第二医院急诊科;温州医科大学护理学院;
【分类号】：R542.22

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