CT前瞻性心电门控技术对先天性心脏病诊断价值的Meta分析

发布时间：2018-05-02 00:11

本文选题：CT + 前瞻性心电门控　；参考：《重庆医科大学》2017年硕士论文

【摘要】：目的:对CT前瞻性心电门控技术诊断先天性心脏病进行Meta分析,评价在先天性心脏病的诊断价值。方法:检索国内外发表的CT前瞻性心电门控技术诊断先天性心脏病的文献进行Meta分析。提取资料,运用Meta-disc1.4软件进行异质性检验,根据是否存在异质性选用不同的效应模型进行合并。绘制森林图,计算合并后的敏感度、特异度、似然比以及曲线下面积(area under curve,AUC)。纳入的文献的质量评价根据Cochrane协作网的质量评价工具(Quality Assessment for Diagnostic Accuracy Studies,QUADAS)进行。结果:共12篇文献被纳入,总计1431处先天性心脏病畸形。CT前瞻性心电门控技术对先天性心脏病诊断灵敏度及特异度均不存在异质性,采用固定效应模型合并后的总敏感度为0.96(95%CI:0.94~0.97)、总特异度为1(95%CI:1.00~1.00)、阳性似然比为365.94(95%CI:231.18~579.26)、阴性似然比0.04(95%CI:0.03~0.05)。SROC曲线下面积为99.86%,Q*指数=0.9879。结论:CT前瞻性心电门控技术对诊断先天性心脏病诊断有较高的敏感度和特异度,同时,受试者工作特征曲线下面积较大,对于先天性心脏病具有较高的和稳定的诊断性能。
[Abstract]:Objective: to evaluate the diagnostic value of CT prospective ECG gated technique in the diagnosis of congenital heart disease (CHD) by Meta analysis. Methods: Meta analysis was performed on CT prospective ECG gated diagnosis of congenital heart disease published at home and abroad. The data were extracted, the heterogeneity was tested by Meta-disc1.4 software, and different effect models were selected according to the existence of heterogeneity. The sensitivity, specificity, likelihood ratio and area under the curve were calculated. The quality evaluation of the included documents was conducted according to the quality Assessment for Diagnostic Accuracy study Quadas of the Cochrane collaboration Network. Results: a total of 12 articles were included and 1431 congenital heart malformations. Ct prospective ECG gating technique had no heterogeneity in the diagnostic sensitivity and specificity of congenital heart disease. The total sensitivity, specificity, positive likelihood ratio and negative likelihood ratio of the fixed effect model were 0.96 ~ 95 CI: 0.94 ~ 0.97, 1 ~ 95 CI: 1.00 ~ 1.00 ~ 1.00, 365.945.94 ~ 95CI: 231.181.181 ~ 579.26 and the area under the 0.04(95%CI:0.03~0.05).SROC curve was 99.86Q* ~ 0.9879, respectively. ConclusionThe sensitivity and specificity of the prospective ECG gating technique in the diagnosis of congenital heart disease are high. At the same time, the area under the operating characteristic curve of the subjects is larger, which has a high and stable diagnostic performance for the congenital heart disease.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R816.2;R541.1

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