纹理分析用于心肌淀粉样变性和肥厚型心肌病鉴别诊断的可行性研究

发布时间：2018-05-03 05:31

  本文选题：纹理分析 + 磁共振成像　； 参考：《放射学实践》2017年12期

【摘要】：目的:评价磁共振成像结合纹理分析技术对心肌淀粉样变性与肥厚型心肌病的鉴别诊断价值。方法:经心内膜活检证实的心肌淀粉样变性轻链型(CA)患者18例及经临床确诊的肥厚型心肌病患者18例,均采用3.0T MR标准化扫描获得电影序列图像,使用TexRad软件对所有患者左心室中段两腔短轴位图像进行取样分析,选择不同的空间缩放因子(SSF,取值为0和2~6),获得在不同纹理过滤尺度下代表纹理特征的5个参数值(包括均值、标准差、峰度、偏度、熵值),采用Mann-Whitney U检验进行组间比较,并使用ROC曲线评估各参数的诊断效能。结果:心肌淀粉样变性和肥厚型心肌病的熵值、峰度和偏度间的差异均有统计学意义(P0.05)。诊断心肌淀粉样变性ROC曲线分析结果显示,SSF=3时取熵值≥2.68,诊断淀粉样变性的曲线下面积最大(0.87),诊断敏度87.2%,特异度为90.9%、符合率为88.0%。结论:纹理分析可用于心肌淀粉样变性和肥厚型心肌病的鉴别诊断,相比传统鉴别方法具有无需使用对比剂且缩短检查时间的优势。
[Abstract]:Objective: to evaluate the value of magnetic resonance imaging (MRI) combined with texture analysis in the differential diagnosis of myocardial amyloidosis and hypertrophic cardiomyopathy. Methods: eighteen patients with myocardial amyloidosis and 18 patients with hypertrophic cardiomyopathy confirmed by endocardial biopsy were studied. TexRad software was used to sample and analyze two lumen short axial images of left ventricular middle segment in all patients. Different spatial scaling factors were selected, the values were 0 and 2 脳 6, and five parameters (including mean value) representing texture feature were obtained at different texture filtering scales. Standard deviation, kurtosis, deviation and entropy were compared by Mann-Whitney U test and ROC curve was used to evaluate the diagnostic efficiency of each parameter. Results: there were significant differences in entropy, kurtosis and bias between myocardial amyloidosis and hypertrophic cardiomyopathy (P 0.05). The results of ROC curve analysis of myocardial amyloidosis showed that the entropy value 鈮，

本文编号：1837206