性别对急性ST段抬高型心肌梗死患者再灌注时间延迟的影响

发布时间：2018-05-14 17:11

本文选题：心肌梗死 + 性别因素　；参考：《解放军医学杂志》2017年02期

【摘要】：目的分析解放军306医院心脏中心急性ST段抬高型心肌梗死(STEMI)救治体系中不同性别患者之间再灌注时间延迟的分布。方法纳入2011年1月-2015年12月解放军306医院连续急诊收治并符合入选标准的STEMI患者325例,依据性别不同分为男性组(268例)和女性组(57例),分析各急救时间,包括发病(SO)至首次医疗接触(FMC)时间(SO-to-FMC)、转运时间(FMC-to-D)、FMC-to-B、导管室启动延迟时间、介入操作延迟时间、急诊至球囊扩张血管再通时间(D-to-B)等,并观察预后。结果尽管女性患者的院前延迟时间中位数(160.0min)和So-to-FMC中位数(100.0min)较男性(分别为119.5min和69.5min)延长,但差异无统计学意义,其余各项再灌注延迟时间差异也无统计学意义(P0.05)。女性患者合并高血压、糖尿病者比例较高,吸烟率明显低于男性(P0.05);两组STEMI患者30d内和1年内的主要心脑血管不良事件(MACCE)发生率(男性5.22% vs 女性5.26%;男性10.82% vs 女性8.77%)差异无统计学意义(P0.05)。结论性别因素对再灌注延迟的影响正逐渐弱化。
[Abstract]:Objective to analyze the distribution of reperfusion time delay among patients of different genders in acute St segment elevation myocardial infarction (STEMI) treatment system in 306 Hospital of PLA. Methods from January 2011 to December 2015, 325 consecutive emergency patients with STEMI admitted to 306 Hospital of PLA from January 2011 to December 2015 were divided into male group (268 cases) and female group (57 cases) according to gender difference. The time of SO-to-FMC, FMC-to-DX, delay of catheterization, delay of interventional operation, time of recanalization from emergency to balloon dilation, etc., and prognosis were observed. Results although the median pre-hospital delay time (160.0min) and So-to-FMC median (100.0mins) in female patients were significantly longer than those in males (119.5min and 69.5 mins, respectively), the difference was not statistically significant, and there was no significant difference in the rest of reperfusion delay time (P 0.05). The incidence of major cardiovascular and cerebrovascular adverse events (5.22% in males vs 5.26% in females; 10.82% in males vs 8.77g% in females) had no significant difference between the two groups in the incidence of major cardiovascular and cerebrovascular adverse events (5.22% vs 5.26%; 10.82% vs 8.77% in females). Conclusion the effect of sex factor on reperfusion delay is weakening gradually.
【作者单位】：解放军306医院心内科;
【分类号】：R542.22

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