白细胞计数与急性ST段抬高型心肌梗死病人直接经皮冠状动脉介入术中无复流的关系

发布时间：2018-06-08 23:31

  本文选题：心肌梗死 + 白细胞　； 参考：《首都医科大学学报》2017年03期

【摘要】：目的探讨白细胞计数与急性ST段抬高型心肌梗死(ST-segment elevation myocardial infarction,STEMI)病人直接经皮冠状动脉介入术(percutaneous coronary intervention,PCI)中无复流的关系。方法选取2013年11月至2015年12月因急性STEMI住院并行直接PCI的病人266例,根据PCI术中无复流发生情况分为正常复流组(A组)242例和无复流组(B组)24例。比较两组病人临床资料特点及住院期间主要不良心血管事件(major adverse cardiovascular events,MACE)发生率,采用Logistic回归分析筛选急性STEMI病人PCI术中无复流的影响因素。结果无复流组白细胞计数、血肌酐明显高于正常复流组(P0.05),Killip≥3级比例显著升高(P=0.009);两组病人住院期间MACE发生率分别为16.7%和2.9%(P=0.001)。多因素Logistic回归分析结果显示白细胞计数(OR=1.220,95%CI:1.064~1.399,P=0.004)、Killip分级(OR=4.617,95%CI:1.093~2.095,P=0.037)是急性STEMI病人PCI术中无复流的独立预测因素。结论入院时白细胞计数是急性STEMI病人PCI术中无复流的独立预测因素,早期检测白细胞计数可以初步评估PCI术中无复流的发生风险。
[Abstract]:Objective to investigate the relationship between leukocyte count and non-reflow in patients with ST-segment elevation myocardial infarction (ST-segment elevation myocardial inflexion) undergoing direct percutaneous coronary intervention (PCI). Methods from November 2013 to December 2015, 266 patients underwent direct PCI due to acute STEMI were divided into two groups: normal reflow group (n = 242) and non-reflow group (n = 24). The characteristics of clinical data and the incidence of major adverse cardiovascular events during hospitalization were compared between the two groups. Logistic regression analysis was used to screen the influencing factors of no reflow in acute STEMI patients. Results the white blood cell count in no reflow group was significantly higher than that in the normal reflow group (P 0.05 Killip 鈮，

本文编号：1997705