二尖瓣环运动参数对心尖肥厚型心肌病左心室功能的评价

发布时间：2018-06-13 04:08

本文选题：二尖瓣环 + 组织多普勒　；参考：《苏州大学》2016年硕士论文

【摘要】：目的应用超声心动图组织多普勒技术(DTI)测定二尖瓣环运动参数,探讨其在评价心尖肥厚型心肌病(AHCM)左心室功能的意义。方法选择43例AHCM患者、30例高血压患者和30例健康体检者。予行常规12导联心电图及超声心动图检查,测量射血分数(LVEF)、二尖瓣口舒张早期、晚期峰值血流速度(E、A)、二尖瓣环收缩期、舒张早期运动速度(Sa、Ea),E/Ea及左室等容舒张时间(IVRT)。结果1.NC组、AHCM组及HBP组间LVEF无显著性差异(p0.05);2.AHCM组Sa明显低于NC组(p0.05),Ea低于HBP组和NC组(p0.05),E/Ea、IVRT高于HBP组和NC组(p0.05);3.HBP组Ea低于NC组(p0.05),E/Ea、IVRT高于NC组(p0.05);4.心尖部厚度与Ea、Sa呈负相关(p0.05),与E/Ea、IVRT呈正相关(p0.05)。结论1.二尖瓣环运动参数可用于AHCM左心室功能的评价;2.Ea、E/Ea、IVRT在一定程度上可以反映舒张功能的变化,心尖部室壁越厚,Ea越低,E/Ea和IVRT越高,舒张功能越差;3.Sa是反映左心室纵向收缩功能的指标,较LVEF评价左室收缩功能变化更为敏感,推测AHCM在LVEF降低前左室收缩功能已有所降低。
[Abstract]:Objective to evaluate the left ventricular function in apical hypertrophic cardiomyopathy (AHCM) by measuring mitral annular motion parameters by tissue Doppler echocardiography (TDI). Methods 43 patients with AHCM and 30 patients with hypertension and 30 healthy controls were selected. Routine 12-lead electrocardiogram and echocardiography were performed to measure the ejection fraction (LVEF), early diastolic velocity of mitral orifice, late peak velocity of mitral valve, mitral annular systolic phase, early diastolic velocity and left ventricular isovolumic diastolic time (IVRTT). Results 1. There was no significant difference in LVEF between NC group and HBP group. 2.The sa of AHCM group was significantly lower than that of NC group (P 0.05). The level of EPA in HBP group and NC group was higher than that in HBP group and NC group (p 0.053.The EA of HBP group was lower than that of NC group. There was a negative correlation between apical thickness and EA, and a positive correlation between apical thickness and E / EA IVRT. Conclusion 1. Mitral annular motion parameters can be used to evaluate the left ventricular function of AHCM. 2. The changes of diastolic function can be reflected by E / E / E _ (IVRT) to some extent, and the thicker the apical ventricular wall is, the lower the E / E _ (a) and IVRT are. The worse the diastolic function is, 3. Sa is the index reflecting the left ventricular longitudinal systolic function, which is more sensitive than LVEF to evaluate the left ventricular systolic function. It is speculated that the left ventricular systolic function of AHCM has decreased before LVEF is decreased.
【学位授予单位】：苏州大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R542.2

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