血清25羟维生素D3与2型糖尿病合并高血压患者的关系

发布时间：2018-06-16 08:08

本文选题：型糖尿病 + 高血压　；参考：《中国老年学杂志》2017年03期

【摘要】：目的探讨血清25羟维生素D3与2型糖尿病(T2DM)合并高血压的关系。方法选取该院96例T2DM患者,分成单纯组(单纯T2DM,46例)、合并组(T2DM合并高血压,50例),选取同期50例健康志愿者为对照组,测定三组血糖、血压、血脂和25羟维生素D3,两组服用维生素D前后测定血糖、血压、血脂和25羟维生素D3水平。结果合并组的收缩压、总胆固醇水平均明显高于单纯组和对照组,单纯组和合并组空腹血糖水平无统计学差异(P0.05)。单纯组、合并组的25羟维生素D3水平明显低于对照组,且合并组最低。25羟维生素D3和收缩压、总胆固醇呈负相关。单纯组、合并组服用维生素D后血糖、血压、血脂和25羟维生素D3水平均得到改善。结论血清25羟维生素D3可能是T2DM并高血压的影响因素。
[Abstract]:Objective to investigate the relationship between serum 25 hydroxyvitamin D 3 and type 2 diabetes mellitus T 2 DM with hypertension. Methods 96 patients with T2DM in this hospital were divided into simple group (46 cases of T2DMN), combined group of 50 cases of T2DM with hypertension and 50 cases of healthy volunteers as control group. Blood glucose and blood pressure were measured in three groups. Blood glucose, blood pressure, blood lipids and 25 hydroxyvitamin D3 levels were measured before and after taking vitamin D. Results the systolic blood pressure and total cholesterol levels in the combined group were significantly higher than those in the simple group and the control group. There was no significant difference in fasting blood glucose level between the simple group and the combined group (P 0.05). The level of 25-hydroxyvitamin D _ 3 in the combined group was significantly lower than that in the control group, and the lowest level of .25-hydroxyvitamin D _ 3 was negatively correlated with systolic blood pressure and total cholesterol in the combined group. Blood glucose, blood pressure, blood lipids and 25 hydroxyvitamin D 3 levels were improved in both groups. Conclusion Serum 25 hydroxyvitamin D 3 may be a risk factor for type 2 DM complicated with hypertension.
【作者单位】：北京积水潭医院;
【分类号】：R587.1

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