原发性高血压患者24小时尿钠钾排泄比与左心室质量指数的相关性研究

发布时间：2018-06-18 20:20

  本文选题：高血压 + 尿钠　； 参考：《中国全科医学》2017年32期

【摘要】：目的探讨原发性高血压患者24 h尿钠、尿钾和24 h尿钠钾排泄比与左心室质量指数(LVMI)的关系。方法选取2015—2016年新疆医科大学第一附属医院心血管内科住院的原发性高血压患者293例,留取其24 h尿标本,检测24 h尿钠、尿钾水平和24 h尿钠钾排泄比。依据24 h尿钠水平将患者分为:A组(尿钠≤100 mmol/24h),B组(100 mmol/24 h尿钠≤200 mmol/24 h)和C组(尿钠200 mmol/24 h)。进行心脏超声心动图检测,记录左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)、室间隔厚度(IVST)、左心室后壁厚度(LVPWT)、左心室射血分数(LVEF)及LVMI。结果 3组患者IVST、LVPWT比较,差异均有统计学意义(P0.05);其中C组IVST大于A组和B组,C组LVPWT大于A组(P0.05)。Spearman相关分析结果显示,LVMI与24 h尿钠钾排泄比呈正相关(rs=0.119,P0.05),与24 h尿钠、尿钾无直线相关性(rs=0.139、0.087,P0.05)。多元线性回归分析结果显示,24 h尿钠钾排泄比是LVMI的影响因素[β(95%CI)=1.287(0.116,2.457),P0.05],24 h尿钠[β(95%CI)=-0.011(-0.050,0.027)]和24 h尿钾[β(95%CI)=0.071(-0.096,0.237)]与LVMI无明显相关性(P0.05)。结论高血压患者24 h尿钠钾排泄比与LVMI相关,独立于血压。
[Abstract]:Objective to investigate the relationship between 24 h urinary sodium, urinary potassium and 24 h urinary sodium potassium excretion ratio and left ventricular mass index (LVMI) in patients with essential hypertension. Methods 293 patients with essential hypertension in the Department of Cardiovascular Medicine of the first affiliated Hospital of Xinjiang Medical University from 2015 to 2016 were selected and their 24 h urine samples were collected. The 24 h urinary sodium, urinary potassium level and 24 h urinary natrium / potassium excretion ratio were measured. According to the 24 h urinary sodium level, the patients were divided into two groups: group A (urine sodium 鈮，

本文编号：2036744