长期传统健身运动对老年高血压患者干预效果的研究

发布时间：2018-06-19 00:19

本文选题：太极拳 + 健身气功　；参考：《扬州大学》2017年硕士论文

【摘要】：研究目的:本文采用太极拳及健身气功运动干预社区老年原发性高血压患者,观察12个月运动干预后对受试者血压、身体成分、血脂、炎症因子、气体信号分子等相关指标的影响,分析该运动对社区老年原发性高血压患者的防治效果、相互关系及相关机理,揭示运动防治高血压的相关机制,拓宽太极拳及健身气功运动对健康促进的研究范畴,使其更好地服务大众健身。研究方法:本研究筛选社区高血压病患者32人(男8名、女24名),平均年龄为63.50±2.91岁,根据患者选择,将其分为运动组和不运动对照组,其中运动组20人,不运动对照组12人;运动组在干预前对每位受试者所测的靶心率与自我疲劳分级制定个体运动强度,施以1h/天、6天/周的小强度太极拳及健身气功运动;分别检测受试者实验前、运动6个月末、运动12个月末的身高、体重、体脂百分比、血压等生理指标以及血脂代谢(甘油三酯、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇),气体信号分子(一氧化氮、一氧化碳、硫化氢),炎症因子(肿瘤坏死因子-α、超敏C反应蛋白、白细胞介素-6),内皮素-1与血管紧张素II等生化指标。研究结果:实验前运动组与对照组的各指标均无统计学差异。(1)运动6个月末,受试者SBP、DBP均出现非常显著性下降(P0.01),且SBP与对照组相比具有显著性差异(P0.05),PP无显著性变化;运动12个月末,SBP、DBP、PP均出现显著性下降(P0.01、P0.05、P0.05),且SBP、PP与对照组相比均有显著性差异(P0.01、P0.05),对照组实验前后无显著性变化。(2)运动6个月末,受试者BMI、体脂率均出现显著性下降(P0.01,P0.05);运动12个月末,体重指数、体脂率均出现非常显著性下降(P0.01),对照组12个月末BMI较实验前出现非常显著性上升(P0.01),而体脂率无显著性差异。(3)运动6个月末,受试者血清HDL-C出现非常显著性上升(P0.01),TC、TG、LDL-C呈下降趋势,但无显著性变化;运动12个月末,TC、TG、LDL-C均出现显著性下降(P0.05、P0.05、P0.01),HDL-C与对照组相比具有显著性差异(P0.05),对照组实验前后无显著性变化。(4)运动6个月末,受试者血清NO、H2S均出现显著性上升(P0.01,P0.05),CO无显著性变化,且H2S与对照组相比具有非常显著性差异(P0.01);运动12个月末,NO、H2S、CO均出现显著性上升(P0.01、P0.05、P0.01),与对照组相比均有显著性差异(P0.05、P0.05、P0.01),对照组实验前后无显著性变化。(5)运动6个月末,受试者血清TNF-α、IL-6均出现非常显著性下降(P0.01),且与对照组相比均有显著性差异(P0.05,P0.01),hs-CRP无显著性变化;运动12个月末,TNF-α、IL-6、hs-CRP均出现非常显著性下降(P0.01),与对照组相比均有显著性差异(P0.01、P0.01、P0.05),对照组实验前后无显著性变化。(6)运动6个月末,受试者血清ET-1、AngⅡ均出现显著性下降(P0.01,P0.05),且ET-1与对照组相比具有显著性差异(P0.05);运动12个月末,ET-1、AngⅡ均出现非常显著性下降(P0.01),与对照组相比均有显著性差异(P0.05),对照组实验前后无显著性变化。(7)运动12个月末,SBP与LDL-C、ET-1、hs-CRP、AngⅡ呈正相关(r=0.49,P0.01;r=0.53,P0.01;r=0.46,P0.05;r=0.39,P0.05),与 NO、CO、HDL-C、H2S 呈负相关(r=0.58,P0.01;r=0.51,P0.01;r0.43,P0.05;r=0.49,P0.05);DBP 与 LDL-C、IL-6 呈正相关(r=0.39,P0.05;r=0.38,P0.05);脉压差与 LDL-C、NO 呈负相关(r=0.51,P0.01;r=0.48,P0.01)。研究结论:通过12个月的太极拳及健身气功运动干预实验研究,1、太极拳及健身气功运动对降低原发性高血压患者的收缩压与舒张压有明显疗效,并缩小脉压差,干预过程中受试者的血压并不是平缓下降,而是波浪式下降。该运动可作为结合药物治疗的辅助降压手段。2、太极拳及健身气功运动有效改善高血压患者BMI指数与体脂率,减少体内多余脂肪;明显降低受试者血清LDL-C、TC和TG水平和升高HDL-C水平,对脂代谢有着积极的调节作用,有效改善血脂异常,降低心血管疾病的发生与发展。3、太极拳及健身气功运动可提高高血压患者血清气体信号分子NO、CO、H2S水平,降低ET-1与AngⅡ水平,改善动脉血管弹性,有效降低血压,促进高血压患者的健康,可作为降压机制之一。4、太极拳及健身气功运动可降低高血压患者血清炎症水平,反映炎症水平的TNF-α、hs-CRP、IL-6均明显降低,降低高血压导致的血管内皮功能损害,从而进一步阻止血压的升高。
[Abstract]:The purpose of this study was to observe the effects of 12 month exercise intervention on the subjects' blood pressure, body composition, blood lipid, inflammatory factors and gas signal molecules after 12 months of exercise intervention, and to analyze the effect of the exercise on the elderly patients with primary hypertension in community. Relationship and related mechanism, reveal the related mechanism of exercise prevention and control of hypertension, broaden the research category of Taijiquan and fitness Qigong exercise to health promotion, make it better serve the public health. Research methods: This study screening 32 people of community hypertension patients (8 men, 24 women), the average age of 63.50 + 2.91 years, according to the choice of the patient, it will be The exercise group was divided into the exercise group and the non exercise control group, of which 20 people in the exercise group and 12 people in the non exercise control group; before the intervention, the exercise intensity was determined by the target rate and the self Fatigue Grade measured by each subjects, and the small intensity Taijiquan and the Fitness Qigong were performed at 1h/ days and 6 days per week. Before the test, the subjects were tested and the exercise was at the end of 6 months, respectively. Physical indexes such as height, weight, body fat percentage, blood pressure, and blood lipid metabolism (triglyceride, total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol), gas signal molecules (nitric oxide, carbon monoxide, hydrogen sulfide), inflammatory factors (tumor necrosis factor - alpha, hypersensitivity C reactive protein, interleukin), and blood lipid metabolism at the end of 12 months of exercise. -6), the biochemical indexes of endothelin -1 and angiotensin II. Results: there was no statistical difference between the pre experiment group and the control group. (1) at the end of the 6 month of the exercise, the subjects had a very significant decrease in SBP and DBP (P0.01), and the SBP had significant difference (P0.05), and the PP had no significant changes compared with the control group, and the exercise was at the end of 12 months, SBP, D. BP, PP were significantly decreased (P0.01, P0.05, P0.05), and SBP, PP was significantly different from the control group (P0.01, P0.05), and there was no significant change in the control group before and after the experiment. (2) the body fat rate decreased significantly (P0.01, P0.05) at the end of the 6 months of exercise (P0.01, P0.05), and the body mass index and body fat rate were very significant at the end of the 12 months of exercise. (P0.01), in the control group, there was a significant increase in BMI at the end of 12 months (P0.01), but there was no significant difference in body fat rate. (3) at the end of the 6 month of the exercise, the serum HDL-C of the subjects increased significantly (P0.01), TC, TG, LDL-C showed a decline, but no significant change; TC, TG, LDL-C were significantly decreased at the end of the 12 months of exercise (P0.05, LDL-C) 05, P0.01), HDL-C was significantly different from the control group (P0.05), and there was no significant change in the control group before and after the experiment. (4) at the end of the 6 month of the exercise, the serum NO, H2S had a significant increase (P0.01, P0.05), CO had no significant changes, and H2S was significantly different from the control group (P0.01); NO, H2S, and H2S were all appeared at the end of the 12 months of exercise. Significantly increased (P0.01, P0.05, P0.01), compared with the control group (P0.05, P0.05, P0.01), no significant changes before and after the control group. (5) at the end of the 6 months of the exercise, the subjects serum TNF- alpha, IL-6 had a very significant decrease (P0.01), and compared with the control group, there were significant differences (P0.05, P0.01), hs-CRP has no significant changes; At the end of the 12 months of exercise, TNF- alpha, IL-6 and hs-CRP were significantly decreased (P0.01), and there were significant differences compared with the control group (P0.01, P0.01, P0.05), and there was no significant change in the control group before and after the experiment. (6) the serum ET-1 and Ang II of the subjects were significantly decreased (P0.01, P0.05) at the end of the 6 months of exercise, and ET-1 was significant compared with the control group. The difference (P0.05); at the end of the 12 months of exercise, both ET-1 and Ang II had a very significant decrease (P0.01), compared with the control group (P0.05), and there was no significant change in the control group before and after the experiment. (7) there was a positive correlation between SBP and LDL-C, ET-1, hs-CRP, Ang II at the end of the 12 months of exercise. C, H2S is negative correlation (r=0.58, P0.01; r=0.51, P0.01; r0.43, P0.05; r=0.49, P0.05); DBP and LDL-C are negative correlation. Research conclusion: through 12 months of Taijiquan and fitness Qigong exercise intervention experimental study, 1, Taijiquan and fitness Qigong Exercise has a significant effect on reducing systolic and diastolic pressure in patients with essential hypertension and narrowing the pulse pressure. The blood pressure of the subjects in the intervention process is not a flat decrease, but a wave type drop. This exercise can be used as an auxiliary antihypertensive method combined with drug therapy.2, Taijiquan and fitness Qigong exercise can effectively improve the BMI finger of hypertensive patients. The number and body fat rate, reduce the excess fat in the body, decrease the serum LDL-C, TC and TG levels and increase the level of HDL-C significantly, have positive regulation on lipid metabolism, improve blood lipid abnormality, reduce the occurrence and development of cardiovascular diseases and.3, Taijiquan and fitness Qigong exercise can improve the serum gas signal molecule NO, CO, H2S level, reducing the level of ET-1 and Ang II, improving arterial elasticity, reducing blood pressure effectively and promoting the health of hypertensive patients, can be used as one of the mechanism of blood pressure lowering.4. Taijiquan and fitness Qigong exercise can reduce the level of serum inflammation in hypertensive patients, which reflect the level of TNF- alpha, hs-CRP, IL-6 in the level of inflammation, and reduce the blood vessels caused by hypertension. Endothelial dysfunction can further prevent blood pressure from rising.
【学位授予单位】：扬州大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R544.1

【参考文献】