延长油田甘谷驿采油厂高血压患病情况分析及其与代谢综合征各组分关系的研究

发布时间：2018-06-21 19:17

本文选题：延长油田甘谷驿采油厂 + 高血压患病率　；参考：《延安大学》2015年硕士论文

【摘要】：【目的】1.调查和研究延长油田甘谷驿采油厂这一特殊工作人群的高血压患病率的情况。2.通过分析不同性别、年龄人群人体测量参数及血生化代谢状态,探讨各代谢综合征各代谢指标与高血压的相关性,为进一步干预治疗提供理论依据。【方法】1.对甘谷驿采油厂职工采取整群抽样的研究方法,进行问卷调查、体格检查以及生化指标检测。在问卷当中涉及到的调查内容具体涉及到被检者姓名、工种、年龄、年龄、饮食习惯、烟酒嗜好、家族病史以及既往病史等。在体格检查的过程当中应用的是统一标准,具体内容包括有身高、体重、臀围、WC以及血压等。在测定生化指标的过程中,先是抽取空腹静脉血实施血糖、TC、TG、LDL-C、HDL-C、UA等相关生化指标检测。针对无糖尿病者要做口服糖耐检验,而身患糖尿病者则是要做馒头餐检验。2.使用Epidata 3.0构建信息数据库,在数据统计分析的过程当中,使用的是spss19.0软件。在资料计量方面,表示为(均数±标准差),两个样本均数对比则应用的是t检验,而多样本之间的均数对比则应用的是方差分析。患病率的对比应用的是χ2检验,并针对危险因素实施Logistic回归分析,其中,α=0.05属于检验水准,如P0.05代表存在显著差异,具备统计学意义。3.观察采油厂职工高血压的总患病率,各自实施不同性别与不同年龄的患病率对比分析,针对血压异常组和血压正常组的相关临床指标(FBS、PBS、TG、TC、UA、BMI、WC、臀围、LDL-C、HDL-C、WHR、WHt R)作出对比分析,对于不同的糖代谢、尿酸代谢、血脂状态以及体质指数之下的高血压患病率进行比较,探讨引起采油厂职工高血压的危险因素并对其进行相关性分析。【结果】1.共调查1290人,1288人资料纳入分析。其中,男性805人,女性483人。查出高血压患病共353人,患病率为27.41%,标化率为19.6%。其中有男性805例,高血压患者266例,患病率33.04%,标化率为24.57%;女性483例,高血压患者87例,其中患病率达到了18.01%,而标化率则是13.4%。男性高血压患病率要超过女性。通过χ2检验分析能够发现,具备显著性差异(χ2=165.65p0.001)。2.将此人群按10岁一个年龄阶段分为5组,20岁~215人,高血压患病率11.16%;30岁~257人,高血压患病率15.95%;40岁~520人,高血压患病率27.50%;50岁~197人,高血压患病率43.66%;60岁~76人,高血压患病率56.58%;70岁~23人,高血压患病率69.57%;总的来说,高血压的患病率有随着年龄的增长有升高的趋势。分析各年龄段男女血压平均水平可以发现,在60岁以前各组血压平均水平都是男性高于女性,到60岁以后,男女血压平均水平没有显著差异。3.高血压患病组的血脂、血尿酸、BMI、WC、臀围、WHR、WHt R等指标均高于血压正常组,差异明显(P0.05)。4.糖尿病前期的血压患病率为44.72%,高于糖代谢正常组的18.79%,糖尿病组合并高血压的患病率达到了48.94%,这比糖代谢正常组要高很多,具备显著性差异(p0.05)。血脂异常组中高TG、高TC、高LDL-C、低HDL-C组中高血压患病率分别为44.95%、56.64%、41.18%、33.53%均高于血脂代谢正常组的28.32%,差异显著(P0.05)。高尿酸合并高血压的患病率为68.75%,高于尿酸正常组患病率的34.84%,差异明显(p0.05)。超重组高血压的患病率为33.77%高于正常组的17.66%,肥胖组高血压患病率达到了57.14%,比正常组明显高一些,存在显著性差异(p0.05)。且肥胖合并高血压组的患病率高于超重组患病率,可见高血压的患病率随体质指数BMI的上升有升高的趋势,且各BMI分组之间差异有统计学意义(p0.05)。5.高血压的单因素非条件Longistic回归的分析,筛选出具有高血压显著相关的影响因素包括:年龄、超重和肥胖、高血糖、高血脂、以及高尿酸。6.高血压危险因素的多因素的非条件Logistic回归分析,把高血压病作为因变量,其他赋值作为自变量,采用向前逐步选择法,以a0.05水平筛选,将年龄、超重和肥胖、高血糖、高血脂、以及高尿酸带入多因素的非条件Logistic回归方程,研究表明,年龄、超重和肥胖、高血糖、高血脂、以及高尿酸是高血压独立危险的因素(P0.05),且各因素危险性排序为:高血脂(OR=2.406)、高血糖(OR=1.807)、肥胖(OR=1.740)、超重(OR=1.633)、高尿酸(OR=1.498)、年龄(OR=1.022)。【结论】1.目前延长油田职工高血压患病率较高,与全国平均水平以及延安平均水平对比而言,都具有显著性差异。高血压的患病率随着年龄增长有增加的趋势,这种增长的趋势与2002年全国调查结果相一致,高血压的患病率表现为:60岁组以前男性显著高于女性,60岁组以后男女患病率差异不大。2.在高血压患病的危险因素当中,排在前面的主要有年龄增加、体重超标、糖脂代谢异常以及高尿酸等。
[Abstract]:[Objective] 1. to investigate and study the prevalence of hypertension in the Gangu post oil production plant of Yanchang oil field. By analyzing the parameters of human body measurement and the state of blood biochemical metabolism in different sex and age groups, the correlation between the metabolic indexes of various metabolic syndrome and hypertension was explored to provide theoretical basis for further intervention. [Methods] [Methods] 1. a questionnaire survey, physical examination and biochemical test were carried out for the staff of Gangu post oil production plant with a cluster sampling. The contents involved in the questionnaire were specifically related to the names of the subjects, age, age, age, age, eating habits, smoking and drinking, family history and previous medical history. In the process of checking, the specific contents include height, weight, hip circumference, WC and blood pressure. In the process of measuring biochemical indicators, the first is to extract fasting blood from blood glucose, TC, TG, LDL-C, HDL-C, UA and other related biochemical indexes. In order to make steamed bread meal test.2. use Epidata 3 to build information database, spss19.0 software is used in the process of statistical analysis of data. In the field of data measurement, it is expressed as (mean standard deviation), and the comparison of two samples is used for t test, while the comparison of the average number between the multiple samples is used for analysis of variance. The contrast application was the chi 2 test, and the Logistic regression analysis was carried out against the risk factors. Among them, the alpha =0.05 belonged to the test level, such as the significant difference between the P0.05 representative and the statistical significance.3. to observe the total prevalence rate of hypertension in the workers of the oil production plant, and to carry out the comparative analysis of the prevalence rate between different sex and the same age, and to counter the abnormal blood pressure group. Comparative analysis of related clinical indicators (FBS, PBS, TG, TC, UA, BMI, WC, WC, hip circumference, LDL-C, HDL-C, WHR, WHt R) was made to compare the different sugar metabolism, uric acid metabolism, blood lipid state and the prevalence of hypertension under body mass index, and to explore the risk factors causing hypertension in the oil production plant and to be related to it. [results] [results] 1. a total of 1290 people were investigated and 1288 people were analyzed. Among them, there were 805 men and 483 women. The prevalence rate of hypertension was 27.41%. The standardized rate was 805 of men, 266 in hypertension, 33.04% for hypertension, 33.04% and 24.57%, 1288 in women and 87 in hypertension, among which the prevalence was reached. 18.01%, and the standardized rate is 13.4%. male hypertension prevalence rate more than women. Through the chi 2 test analysis can be found, with significant differences (x 2=165.65p0.001).2., the population is divided into 5 groups at the age of 10, 20 year old ~215, 11.16% of hypertension, 30 years old to 257, the prevalence of hypertension is 15.95%; 40 years of ~520 people, hypertensive patients The rate of disease was 27.50%; the prevalence rate of hypertension was 43.66% at 50 years old; the incidence of hypertension was 60 years old; the prevalence rate of hypertension was 56.58%; 70 years old ~23, and the prevalence rate of hypertension was 69.57%; in general, the prevalence of hypertension increased with age. The average level of blood pressure in each age group was found to be found before 60 years old. The average blood pressure level before 60 years old was all The average blood pressure level of men and women was no significant difference between men and women after 60 years of age. The blood pressure, blood uric acid, BMI, WC, hip circumference, WHR, WHt R and other indexes were higher than those of normal blood pressure group. The difference was obvious (P0.05), the prevalence rate of blood pressure in pre diabetes was 44.72%, higher than that of normal glucose metabolism group, and the combination and higher diabetes group was higher than that of the normal glucose metabolism group (18.79%). The prevalence of blood pressure was 48.94%, which was much higher than the normal glucose metabolism group, with significant difference (P0.05). High TG, high TC, high LDL-C in dyslipidemia group, 56.64%, 41.18% and 33.53% in the low HDL-C group were respectively higher than 28.32% in the normal blood lipid metabolism group (P0.05). High uric acid combined with hypertension. The rate of disease was 68.75%, which was higher than that of the normal uric acid group (34.84%), the difference was significant (P0.05). The prevalence rate of hyperrecombinant hypertension was 33.77% higher than that of the normal group (17.66%). The prevalence of hypertension in the obese group was 57.14%, higher than that in the normal group (P0.05). The prevalence rate of obesity combined with hypertension was higher than that of the hyperrecombinant hypertension group. The prevalence of hypertension was shown to increase with the increase in the body mass index BMI, and the difference between the BMI groups was statistically significant (P0.05) for the single factor unconditional Longistic regression of.5. hypertension, and the factors that were significantly associated with hypertension included age, overweight and obesity, hyperglycemia, hyperlipidemia, and Non conditional Logistic regression analysis of the risk factors of high uricuric acid.6. hypertension, using the hypertension as the dependent variable and the other assignment as the independent variable, using the forward stepwise selection method to screen the age, overweight and obesity, hyperglycemia, hyperlipidemia, and the non conditional Logistic regression equation with high uric acid and high uric acid into the a0.05, and study the non conditional Logistic regression equation. Age, overweight and obesity, hyperglycemia, hyperlipidemia, and high uric acid are the risk factors for independent hypertension (P0.05), and the risk factors of all factors are hyperlipidemia (OR=2.406), hyperglycemia (OR=1.807), obesity (OR=1.740), overweight (OR=1.633), high uric acid (OR=1.498), and age (OR=1.022). [Conclusion] 1. at present, hypertension in oil field workers is prolonged. The prevalence rate was higher, compared with the national average level and the average level in Yanan. The prevalence of hypertension increased with age, which was consistent with the national survey in 2002. The prevalence of hypertension in the 60 year old group was significantly higher than that in the female, 60 year old group. There was no difference in the prevalence of male and female patients with.2. in the risk factors of hypertension. The leading factors included age increase, overweight, abnormal glycolipid metabolism, and high uric acid.
【学位授予单位】：延安大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R544.1;R589

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