血清尿酸与冠心病传统危险因素的相关性

发布时间：2018-06-22 04:20

本文选题：冠心病 + 尿酸　；参考：《实用医学杂志》2017年11期

【摘要】：目的:探讨血清尿酸与冠心病传统危险因素的关系。方法:利用问卷调查收集研究对象的基本情况,测量血压、身高及体质量。采集空腹静脉血检测血糖、血脂、血清尿酸等指标。采用SPSS 20.0进行统计分析,通过相关性分析血清尿酸与冠心病的传统危险因素的关系。结果:冠心患者群中尿酸的平均值为6.3 mg/d L,男性血清尿酸水平明显高于女性,血清尿酸与体质量指数(r=0.137,P0.001)、收缩压(r=0.053,P=0.025)和甘油三酯(r=0.188,P0.001)有正相关关联,与高密度脂蛋白胆固醇(r=-0.146,P0.001)和估计的肾小球滤过率(r=-0.340,P0.001)有负相关关联,血清尿酸在男性、吸烟、饮酒、慢性CAD的患者中较高,运动时间30 min的体内尿酸水平要比没有运动或运动时间30 min的低。结论:血清尿酸的升高和体质量指数、收缩压、甘油三酯、高密度脂蛋白胆固醇、估计的肾小球滤过率、男性、吸烟、慢性CAD有关联。
[Abstract]:Objective: To investigate the relationship between serum uric acid and the traditional risk factors of coronary heart disease. Methods: the basic situation of the subjects was collected by questionnaire survey, blood pressure, height and body mass were measured. The indexes of blood glucose, blood lipid and serum uric acid were measured by fasting venous blood. SPSS 20 was used to analyze the serum uric acid and coronary heart disease by correlation analysis. The average value of uric acid in crowns was 6.3 mg/d L, and the level of uric acid in male serum was significantly higher than that in women. Serum uric acid and body mass index (r=0.137, P0.001), systolic pressure (r=0.053, P=0.025) and triglyceride (r=0.188, P0.001) were positively correlated with high density lipoprotein cholesterol (r=-0.146, P0.00). 1) there was a negative correlation with estimated glomerular filtration rate (r=-0.340, P0.001). Serum uric acid was higher in men, smoking, drinking, and chronic CAD. The level of uric acid in the body of 30 min was lower than that of no exercise or exercise time 30 min. Conclusion: the increase of serum uric acid and body mass index, systolic pressure, triglyceride, high density fat Protein cholesterol was estimated to be associated with glomerular filtration rate, male smoking, and chronic CAD.
【作者单位】：南方医科大学;广州军区广州总医院心内科;广东省深圳孙逸仙心血管医院;
【基金】：国家自然科学基金资助项目(编号:81402671) 广东省科技计划项目(编号:2013B021800054)
【分类号】：R541.4

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