益气活血祛痰法治疗左心相关性肺动脉高压的临床观察

发布时间：2018-06-24 11:42

本文选题：益气活血祛痰 + 左心相关性肺动脉高压　；参考：《世界中西医结合杂志》2015年12期

【摘要】：目的观察益气活血祛痰法治疗左心相关性肺动脉高压(PH)患者的临床疗效。方法选取左心相关性PH患者60例,随机分为两组,对照组给予常规治疗,包括利尿、抗凝、吸氧以及正性肌力药。治疗组在常规治疗的基础上加用益气活血祛痰法方药。观察两组患者治疗后临床疗效、中医症状积分、6 min步行实验(6MWT)距离、肺动脉收缩压(s PAP)改善情况及安全性分析。结果治疗组患者治疗后总有效率为90.0%,显著高于对照组(70.0%),两组比较差异有统计学意义(P0.05)。两组患者治疗后临床症状积分、6MWT、s PAP均有所改善,治疗组改善程度明显优于对照组,差异具有统计学意义(P0.05)。两组患者在试验期间,均无死亡、病重等事件发生,未出现明显异常,未出现明显的毒副作用。结论益气活血祛痰法中药能显著改善左心相关性PH患者的临床症状,明显改善患者的运动能力,提高患者的生存质量,对临床具有指导意义,值得推广。
[Abstract]:Objective to observe the clinical effect of invigorating qi and activating blood circulation and expelling phlegm in patients with left heart associated pulmonary hypertension (PH). Methods 60 patients with left ventricular associated PH were randomly divided into two groups. The control group was treated with diuretic, anticoagulant, oxygen inhalation and positive inotropic drugs. Treatment group on the basis of routine treatment plus Qi-activating blood-expelling phlegm prescription. The clinical effect, the distance of 6 min walking test (6MWT), the improvement of pulmonary artery systolic pressure (sPAP) and the safety analysis were observed. Results the total effective rate of the treatment group was 90.0%, which was significantly higher than that of the control group (70.0%). The difference between the two groups was statistically significant (P0.05). After treatment, the clinical symptom scores of the two groups were improved, the improvement degree of the treatment group was significantly better than that of the control group, the difference was statistically significant (P0.05). There was no death, serious disease, no obvious abnormality and no obvious side effects in both groups. Conclusion the method of supplementing qi and activating blood circulation and expelling phlegm can significantly improve the clinical symptoms of patients with PH associated with the left heart, improve the exercise ability of the patients, improve the quality of life of the patients, and have a guiding significance for the clinical practice, which is worth popularizing.
【作者单位】：辽宁中医药大学附属医院;
【基金】：辽宁省教育厅一般项目(L2013358)
【分类号】：R259

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