脉管复康片治疗多发性大动脉炎的临床疗效观察

发布时间：2018-07-12 12:00

本文选题：脉管复康片 + 气滞血瘀　；参考：《黑龙江中医药大学》2017年硕士论文

【摘要】：目的:观察脉管复康片对多发性大动脉炎患者的临床疗效。方法:选取黑龙江中医药大学附属第一医院周围血管科2016年03月-2017年02月门诊及病房收治的32例多发性大动脉炎患者,随机分为:治疗组、对照组两组,对照组16例给予一般治疗。治疗组16例在一般治疗基础上同时加服脉管复康片:一次4片,3次/d,治疗疗程为期1个月。治疗前后进行治疗组及对照组的症状及实验室指标(ESR、CRP)的比较。通过体征评分和治疗情况进行观察和分析。结果:本实验所选取的多发性大动脉炎32例患者,年龄平均(28.04±8.01)岁,最小14岁,最大39岁。其中男性6例,女性26例,男女比例1:4.3。经过为期1个月的治疗后,临床观察结果为:对照组:患者16例,治愈0例,显效5例,有效7例,无效4例,总有效率75%;治疗组:患者16例,治愈0例,显效7例,有效9例,无效2例,总有效率87.5%。在观察指标方面,治疗组治疗C反应蛋白、红细胞沉降率,超声下血管壁厚度和管壁狭窄程度经统汁学分析,P0.05,有明显性差异,说明脉管复康片对多发性大动脉炎患者的治疗显著。在症状及体征评分方面,多发性大动脉炎患者,经过脉管复康片治疗后,症状和体征总评分均下降明显,患者头晕、乏力、发热、及颈部疼痛症状在治疗前与治疗后明显缓解,颈动脉杂音、搏动及桡动脉搏动体征试验组及对照组比较则无明显差异(P0.05)。说明脉管复康片治疗多发性大动脉炎患者的临床症状及体征改善明显,能够提高患者生活质量。结论:1.脉管复康片联合丹参川芎嗪注射液和红花黄色素氯化钠注射液对对多发性大动脉炎患者颈部动脉血流有较明显的改善。2.脉管复康片能够降低ESR、CRP指标的表达。3.脉管复康片联合丹参川芎嗪注射液和红花黄色素氯化钠注射液对气滞血瘀型多发性大动脉炎患者临床效果良好。
[Abstract]:Objective: to observe the clinical effect of Vascular Fukang tablet on patients with polyarteritis. Methods: Thirty-two patients with polyarteritis were randomly divided into two groups: treatment group and control group, from March 2016 to February 2017 in peripheral vascular department of the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine. In the control group, 16 cases were given general treatment. In the treatment group, 16 cases were treated with Vascular Fukang tablets on the basis of general treatment: 4 tablets per day, 3 times / d, for one month. The symptoms and laboratory indexes (ESR-CRP) of the treatment group and the control group were compared before and after treatment. Observation and analysis were carried out through physical sign score and treatment. Results: the average age of 32 patients with Takayasu arteritis was (28.04 卤8.01) years old, the youngest was 14 years old and the oldest was 39 years old. There were 6 males and 26 females, and the ratio of males to females was 1: 4.3. After one month of treatment, the results of clinical observation were as follows: control group: 16 cases, cure 0 cases, remarkable effect 5 cases, effective 7 cases, ineffective 4 cases, total effective rate 750.The treatment group: 16 cases, cured 0 cases, remarkable effect 7 cases, treatment group: 16 cases, cured 0 cases, remarkable effect 7 cases, treatment group: 16 cases, cured 0 cases, remarkable effect 7 cases. The total effective rate was 87.5%. There were significant differences in C-reactive protein (CRP), erythrocyte sedimentation rate, thickness of vascular wall and stenosis degree of vessel wall under ultrasound in the treatment group (P 0.05). The treatment of Vascular Fukang tablets for patients with multiple arteritis is significant. In the aspect of symptom and sign score, the total score of symptoms and signs of patients with multiple arteritis after treatment with Vascular Fukang tablets decreased significantly. The symptoms of dizziness, fatigue, fever, and neck pain were obviously alleviated before and after treatment. There was no significant difference in carotid murmur pulsation and radial pulsation signs between the experimental group and the control group (P0.05). It indicated that the clinical symptoms and signs of the patients with multiple arteritis were improved obviously and the quality of life of the patients could be improved. Conclusion 1. Vascular Fukang tablets combined with salvia miltiorrhiza ligustrazine injection and safflower yellow sodium chloride injection can significantly improve the carotid artery blood flow in patients with multiple arteritis. Vascular Fukang tablets can reduce the expression of CRP. 3. Vascular Fukang tablets combined with salvia miltiorrhiza ligustrazine injection and safflower yellow sodium chloride injection had good clinical effect on patients with multiple arteritis with Qi stagnation and blood stasis.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R543.5

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