高血压患者颈动脉内膜中膜厚度与动态血压参数的关系

发布时间：2018-07-22 19:47

【摘要】：目的探讨高血压患者颈动脉内膜中膜厚度(IMT)与动态血压参数的关系。方法选择2014年7月至2015年12月石河子大学医学院第一附属医院收治的高血压患者94例,根据颈动脉超声结果分为单一斑块组和多发斑块组,同时根据超声中IMT的数值,将患者分为IMT正常组和IMT增厚组,另外根据动态血压监测(ABPM)检查结果分为杓型组和非杓型组。应用彩色超声心动图仪测量IMT值,并采用动态血压监测仪对患者进行24 h ABPM检测,记录各项动态血压参数。对比分析不同分组IMT值和动态血压参数及IMT值与动态血压参数的相关性。结果与单一斑块组相比,多发斑块组动态血压参数和IMT水平明显升高(P0.05);杓型组明显低于非杓型组(P0.05);IMT增厚组各动态血压参数明显高于IMT正常组(P0.05);颈动脉IMT值与24 h平均收缩压(SBP)、24 h平均舒张压(DBP)、白昼SBP(d SBP)、夜间SBP(n SBP)、d DBP、n DBP及24 h平均脉压(PP)呈正相关(r=0.723、0.694、0.731、0.689、0.703、0.711、0.756,P=0.028、0.038、0.025、0.040、0.035、0.032、0.018)。结论老年高血压患者中多发性斑块及非杓型均是造成动态血压参数和IMT数值升高的原因;同时,IMT增厚也是诱发动态血压参数升高的原因,且两者之间存在良好的正相关,为临床上治疗老年高血压患者提供新的思路。
[Abstract]:Objective to investigate the relationship between carotid intima media thickness (IMT) and ambulatory blood pressure in patients with hypertension. Methods from July 2014 to December 2015, 94 patients with hypertension were selected from the first affiliated Hospital of Shihezi University Medical College. According to the results of carotid ultrasound, 94 patients were divided into single plaque group and multiple plaque group. The patients were divided into IMT normal group and IMT thickening group. In addition, the patients were divided into dipper group and non-dipper group according to the results of ambulatory blood pressure monitoring (ABPM). IMT was measured by color echocardiography and ambulatory blood pressure (ABPM) was measured by ambulatory blood pressure monitor (ABPM) for 24 hours. The parameters of ambulatory blood pressure were recorded. The IMT values, ambulatory blood pressure parameters and the correlation between IMT values and ambulatory blood pressure parameters in different groups were compared and analyzed. Results compared with single plaque group, The ambulatory blood pressure parameters and IMT levels in multiple plaque group were significantly higher than those in non-dipper group (P0.05), the dynamic blood pressure parameters in IMT thickening group were significantly higher than those in IMT normal group (P0.05), the carotid IMT value and 24 h mean systolic pressure (SBP) were significantly higher than those in normal IMT group (P0.05), and the mean diastolic blood pressure (24 h) in dipper group was significantly lower than that in non-dipper group (P0.05). Pressure (DBP), daytime SBP (d SBP), nocturnal SBP (n SBP) and 24 h mean pulse pressure (PP) were positively correlated (r = 0.7230.694U 0.689 ~ 0.703 ~ 0.703 ~ (0.711) ~ (0.711) ~ (0.756) ~ (0.028) 0.038 ~ (0.025) ~ 0.040 ~ 0.035 ~ 0.035 ~ (0.032) ~ (18). Conclusion multiple plaque and non-dipper type are the causes of the increase of ambulatory blood pressure parameters and IMT values in elderly patients with hypertension, and the thickening of IMT is also the cause of inducing the increase of ambulatory blood pressure parameters, and there is a good positive correlation between them. To provide new ideas for clinical treatment of elderly patients with hypertension.
【作者单位】：石河子大学医学院第一附属医院心内科;
【分类号】：R544.1

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