乌梅消食颗粒治疗缺铁性贫血细胞免疫紊乱的临床观察
发布时间：2018-08-03 13:04
【摘要】：目的:观察乌梅消食颗粒对缺铁性贫血(IDA)患者T细胞亚群的紊乱的治疗疗效。方法:对不同诱因导致的缺铁性贫血患者共85例随机分为两组,治疗组采用乌梅消食颗粒联合乳酸亚铁口服液,对照组采用安慰剂加乳酸亚铁口服液治疗,采用三色直接荧光法流式细胞技术进行T细胞亚群检验,对比二者治疗前后是否具有差异。判断联合治疗及单药治疗对细胞免疫是否具有相关影响。结果:与铁剂单药对照组相比,联合治疗组外周血中CD_3~+、CD_3~+CD_4~+淋巴细胞计数回升更快,CD_4~+/CD_8~+比值较治疗前提升更加明显(P0.01),联合组CD_3~+CD_8~+淋巴细胞计数降低更加明显(P0.05)。与治疗前相比,两组患者细胞免疫紊乱均有所改善(P0.05)。结论:缺铁性贫血患者存在细胞免疫紊乱,而且这种T细胞亚群异常可以被铁剂纠正,联合乌梅消食颗粒可以加速这种细胞免疫异常的恢复。
[Abstract]:Objective: to observe the therapeutic effect of Wumei Xiaoshi granule on the disorder of T cell subsets in (IDA) patients with iron deficiency anemia. Methods: a total of 85 patients with iron deficiency anemia caused by different inducements were randomly divided into two groups: the treatment group was treated with Wumei Xiaoshi granule combined with ferrous lactate oral solution, and the control group was treated with placebo plus ferrous lactate oral solution. The T cell subsets were detected by three color direct fluorescence flow cytometry, and the difference was compared before and after treatment. To determine whether combined therapy or monotherapy has a related effect on cellular immunity. Results: compared with the control group, the CD3 ~ CD4 ~ + lymphocyte count in the combined treatment group increased more rapidly than that in the control group (P0.01), and the CD3 ~ CD8 ~ lymphocyte count in the combined group decreased more significantly than that before the treatment (P0.05). Compared with before treatment, the two groups of patients with cellular immune disorders improved (P0.05). Conclusion: there is cellular immune disorder in patients with iron deficiency anemia, and the abnormal T cell subsets can be corrected by iron, and combined with Wumei Xiaoshi granule can accelerate the recovery of this abnormal cellular immunity.
【作者单位】： 廊坊市中医医院中国中医血液病专病诊疗中心;
【分类号】：R556.3
，
本文编号：2161831
[Abstract]:Objective: to observe the therapeutic effect of Wumei Xiaoshi granule on the disorder of T cell subsets in (IDA) patients with iron deficiency anemia. Methods: a total of 85 patients with iron deficiency anemia caused by different inducements were randomly divided into two groups: the treatment group was treated with Wumei Xiaoshi granule combined with ferrous lactate oral solution, and the control group was treated with placebo plus ferrous lactate oral solution. The T cell subsets were detected by three color direct fluorescence flow cytometry, and the difference was compared before and after treatment. To determine whether combined therapy or monotherapy has a related effect on cellular immunity. Results: compared with the control group, the CD3 ~ CD4 ~ + lymphocyte count in the combined treatment group increased more rapidly than that in the control group (P0.01), and the CD3 ~ CD8 ~ lymphocyte count in the combined group decreased more significantly than that before the treatment (P0.05). Compared with before treatment, the two groups of patients with cellular immune disorders improved (P0.05). Conclusion: there is cellular immune disorder in patients with iron deficiency anemia, and the abnormal T cell subsets can be corrected by iron, and combined with Wumei Xiaoshi granule can accelerate the recovery of this abnormal cellular immunity.
【作者单位】： 廊坊市中医医院中国中医血液病专病诊疗中心;
【分类号】：R556.3
，
本文编号：2161831
本文链接：https://www.wllwen.com/yixuelunwen/xxg/2161831.html
最近更新
教材专著
