扩张型心肌病患者恶性室性心律失常与心率变异性的相关性分析
发布时间：2018-08-08 12:02
【摘要】：目的:探究与分析扩张型心肌病患者恶性室性心律失常与心率变异性的相关性。方法:选取我院自2015年1月至2017年1月收治的90例扩张型心肌病患者作为观察组,另选择同时期收治的来我院体检的90例正常成年人作为对照组,采用24h动态心电图对两组患者的心率变异性以及恶性室性心律失常发生情况,按照是否发生了恶性心律失常将观察组分为恶性室性心律失常阳性组(n=47例)与恶性室性心律失常阴性组(n=43例),对比各组心率的差异,探讨扩张型心肌病患者恶性室性心律失常与心率变异性的相关性。结果:对照组与观察组性别、年龄、病程、收缩压、舒张压、心率、血清钠、血清钾、血清钙及空腹血糖相比无明显差异(P0.05)。观察组与对照组相比血肌酐升高,尿酸升高,前体N末端前脑利钠肽升高,心功能分级升高,左室射血分数低,左室舒张末内径高,差异具有统计学意义(P0.05)。恶性室性心律失常阳性组与恶性心律失常阴性组的性别、年龄、病程、收缩压、舒张压、心率、血清钠、血清钾、血清钙及空腹血糖相比无明显差异(P0.05)。恶性室性心律失常阳性组与恶性心律失常阴性组相比血肌酐升高,尿酸升高,前体N末端前脑利钠肽升高,心功能分级升高,左室射血分数低,左室舒张末内径高,差异具有统计学意义(P0.05)。观察组与对照组相比SDNN低、SDANN低、r MSSD低、PNN50高,差异具有统计学意义(P0.05)。恶性室性心律失常阳性组与恶性室性心律失常阴性组SDNN低、SDANN低、r MSSD低、PNN50高,差异具有统计学意义(P0.05)。对照组、恶性室性心律失常阴性组及恶性室性心律失常阳性组,随着病情的加重SNDD、SDANN、r MSSD随之降低,PNN50升高,呈现出明显的相关性(P0.05)。结论:心率变异性可作为一种重要的指标用来预测扩张型心肌病患者恶性室性心律失常的发生情况,当心率变异性降低时可与扩张型心肌病恶性室性心律失常的发生有关。
[Abstract]:Objective: to investigate and analyze the relationship between malignant ventricular arrhythmia and heart rate variability in patients with dilated cardiomyopathy. Methods: 90 patients with dilated cardiomyopathy treated in our hospital from January 2015 to January 2017 were selected as observation group, and 90 healthy adults admitted to our hospital during the same period as control group. Heart rate variability (HRV) and the incidence of malignant ventricular arrhythmias were studied by 24 h ambulatory electrocardiogram (ECG). According to whether malignant arrhythmia occurred, the observation group was divided into positive group (n = 47) and negative group (n = 43). To investigate the relationship between malignant ventricular arrhythmia and heart rate variability in patients with dilated cardiomyopathy. Results: there was no significant difference in sex, age, course, systolic blood pressure, diastolic blood pressure, heart rate, serum sodium, serum potassium, serum calcium and fasting blood glucose between the control group and the observation group (P0.05). Compared with the control group, the serum creatinine, uric acid, precursor N-terminal forebrain natriuretic peptide, cardiac function grade, left ventricular ejection fraction and left ventricular end-diastolic diameter were significantly higher in the observation group than in the control group (P0.05). There was no significant difference in sex, age, course of disease, systolic blood pressure, diastolic blood pressure, heart rate, serum sodium, serum potassium, serum calcium and fasting blood glucose between positive group and negative group (P0.05). Serum creatinine, uric acid, precursor N-terminal forebrain natriuretic peptide, cardiac function grade, left ventricular ejection fraction and left ventricular end-diastolic diameter were increased in malignant ventricular arrhythmia positive group compared with those in malignant arrhythmia negative group. The difference was statistically significant (P0.05). Compared with the control group, the SDNN of the observation group was lower than that of the control group (P0.05). There was a significant difference between the positive group of malignant ventricular arrhythmias and the negative group of malignant ventricular arrhythmia (P 0.05). The SDNN low SDANN low r MSSD low PNN50 was higher in the malignant ventricular arrhythmia positive group than that in the malignant ventricular arrhythmia negative group (P0.05). In control group, negative group of malignant ventricular arrhythmias and positive group of malignant ventricular arrhythmia, with the exacerbation of the disease, the SDANNNr MSSD decreased with the increase of PN50, showing a significant correlation (P0.05). Conclusion: heart rate variability can be used as an important index to predict the occurrence of malignant ventricular arrhythmias in patients with dilated cardiomyopathy, and may be related to the occurrence of malignant ventricular arrhythmias in dilated cardiomyopathy when heart rate variability decreases.
【学位授予单位】：西安医学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R542.2;R541.7
本文编号：2171730
[Abstract]:Objective: to investigate and analyze the relationship between malignant ventricular arrhythmia and heart rate variability in patients with dilated cardiomyopathy. Methods: 90 patients with dilated cardiomyopathy treated in our hospital from January 2015 to January 2017 were selected as observation group, and 90 healthy adults admitted to our hospital during the same period as control group. Heart rate variability (HRV) and the incidence of malignant ventricular arrhythmias were studied by 24 h ambulatory electrocardiogram (ECG). According to whether malignant arrhythmia occurred, the observation group was divided into positive group (n = 47) and negative group (n = 43). To investigate the relationship between malignant ventricular arrhythmia and heart rate variability in patients with dilated cardiomyopathy. Results: there was no significant difference in sex, age, course, systolic blood pressure, diastolic blood pressure, heart rate, serum sodium, serum potassium, serum calcium and fasting blood glucose between the control group and the observation group (P0.05). Compared with the control group, the serum creatinine, uric acid, precursor N-terminal forebrain natriuretic peptide, cardiac function grade, left ventricular ejection fraction and left ventricular end-diastolic diameter were significantly higher in the observation group than in the control group (P0.05). There was no significant difference in sex, age, course of disease, systolic blood pressure, diastolic blood pressure, heart rate, serum sodium, serum potassium, serum calcium and fasting blood glucose between positive group and negative group (P0.05). Serum creatinine, uric acid, precursor N-terminal forebrain natriuretic peptide, cardiac function grade, left ventricular ejection fraction and left ventricular end-diastolic diameter were increased in malignant ventricular arrhythmia positive group compared with those in malignant arrhythmia negative group. The difference was statistically significant (P0.05). Compared with the control group, the SDNN of the observation group was lower than that of the control group (P0.05). There was a significant difference between the positive group of malignant ventricular arrhythmias and the negative group of malignant ventricular arrhythmia (P 0.05). The SDNN low SDANN low r MSSD low PNN50 was higher in the malignant ventricular arrhythmia positive group than that in the malignant ventricular arrhythmia negative group (P0.05). In control group, negative group of malignant ventricular arrhythmias and positive group of malignant ventricular arrhythmia, with the exacerbation of the disease, the SDANNNr MSSD decreased with the increase of PN50, showing a significant correlation (P0.05). Conclusion: heart rate variability can be used as an important index to predict the occurrence of malignant ventricular arrhythmias in patients with dilated cardiomyopathy, and may be related to the occurrence of malignant ventricular arrhythmias in dilated cardiomyopathy when heart rate variability decreases.
【学位授予单位】：西安医学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R542.2;R541.7
【参考文献】
相关期刊论文 前10条
1 陈新胜;柯植泉;;原发性高血压合并左心室肥厚与心率变异性及室性心律失常的相关性研究[J];临床医学工程;2016年07期
2 付生弟;;肥厚型心肌病病人心率变异性及心律失常分析[J];中西医结合心脑血管病杂志;2016年13期
3 张炜;党爱民;樊晓寒;陈柯萍;张澍;;扩张型心肌病心脏性猝死患者临床特征分析[J];中华心律失常学杂志;2016年03期
4 李坚;;HRV及QTV与急性心肌梗死部位及恶性室性心律失常的相关性分析[J];黑龙江医药;2016年02期
5 袁鼎;陈国方;蔡小婕;江隆福;;急性冠状动脉综合征强化他汀治疗对术后室性心律失常及心率变异性的影响[J];心电与循环;2016年02期
6 刘晶;韩琳;高喜军;;心率变异性及QT间期变异性与急性心肌梗死患者病情严重程度、预后及室性心律失常的关系研究[J];实用心脑肺血管病杂志;2015年12期
7 覃晓波;陈蒙华;;维持性血液透析患者心率变异性与室性心律失常的研究进展[J];实用心电学杂志;2015年03期
8 孟昊;胡元会;宋庆桥;褚瑜光;魏艺;贾岱琳;张菀桐;李可;;老年高血压患者左心室肥厚与心律失常及心率变异性的关系研究[J];中国心血管病研究;2015年01期
9 沈国英;金智敏;;心率变异性与急性心肌梗死部位的临床分析[J];重庆医科大学学报;2014年10期
10 杨新;杨燕;许国军;;室性心律失常患者心率变异性研究[J];临床心电学杂志;2014年02期
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