血管生成素样蛋白-4与急诊经皮冠状动脉介入无复流现象的相关性

发布时间：2018-08-27 09:20

【摘要】：目的探讨急性ST段抬高型心肌梗死(STEMI)患者血管生成素样蛋白(Angptl)-4血清水平与在进行首次急诊经皮冠状动脉介入(PCI)手术后无复流现象之间的关系。方法 41例首次发生急性STEMI患者,入院后均按指南要求行急诊PCI。根据校正的TIMI血流分级(CTFC)将患者分为无复流组(CTFC≥40帧)和对照组(CTFC40帧),抽取入院时血样,检测Angptl-4。对出现无复流的危险因素进行Logistic分析。结果①两组患者在肌酸激酶峰值、N末端脑钠肽前体(NT-proB NP)峰值、罪犯血管、高敏C反应蛋白(hs-CRP)、Angptl-4水平存在显著差异(P0.05)。②NT-proB NP、hs-CRP及Angptl-4水平与心肌梗死患者是否出现无复流密切相关(OR=3.967,P0.05;OR=2.737,P0.05;OR=0.468,P0.05)。结论Angptl-4水平与CTFC评价的急诊PCI手术患者的无复流现象有关,其可能具有改善无复流的作用。
[Abstract]:Objective to investigate the relationship between the serum level of angiopoietin-like protein (Angptl) -4) in patients with acute ST segment elevation myocardial infarction (STEMI) and no reflow after the first emergency percutaneous coronary intervention (PCI). Methods 41 patients with acute STEMI were treated with emergency PCI. according to the guidelines. Patients were divided into no reflow group (CTFC 鈮，

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