2006年、2011年中国城市医院经桡动脉冠状动脉介入治疗情况分析——China PEACE回顾性CathPCI研究结果

发布时间：2018-10-12 12:43

【摘要】：目的:分析2006年、2011年中国城市医院经桡动脉经皮冠状动脉介入治疗(PCI)患者的临床特征、治疗模式和院内结局的变化。方法:使用"冠心病医疗结果评价和临床转化研究"——回顾性冠状动脉(冠脉)造影和PCI研究(China PEACE回顾性Cath PCI研究)的数据,分析两阶段随机抽样获得的2006年和2011年有代表性的城市医院行经桡动脉PCI患者的临床信息,并对每年度的数据分别进行加权计算。结果:来自53家医院的3 301例病例纳入分析。2006~2011年5年间经桡动脉PCI的住院患者数增加7倍。与2006年相比,2011年患者女性比例和平均年龄有所增高(P均0.05);到院时合并肾功能不全[估计肾小球滤过率60 ml/(min·1.73 m2)]和心力衰竭者有所减少(P均0.05);冠脉病变呈单支病变者减少,而三支病变和左主干病变者增多(P均0.01)。2006~2011年间,PCI干预病变的部位分布无明显变化;药物洗脱支架的使用率呈显著增高(P0.001),2011年为97.7%;抗栓和他汀类药物的使用率普遍显著增加。2006年、2011年患者住院时长分别为1(07,15)天和11(7,14)天(P0.05)。与2006年相比,2011年穿刺部位出血的发生率显著下降(P0.01),其余院内不良事件均无显著变化。结论:2006~2011年间,我国城市医院行经桡动脉PCI手术量迅猛增加,患者临床特征和治疗模式均发生了显著变化,我国经桡动脉介入治疗技术日趋成熟和常规化。
[Abstract]:Objective: to analyze the changes of clinical features, treatment patterns and hospital outcomes in patients with (PCI) treated by percutaneous coronary intervention (PCI) via radial artery in China City Hospital in 2006 and 2011. Methods: the data of retrospective coronary angiography (CAG) and PCI (China PEACE retrospective Cath PCI study) were used to evaluate the medical outcome and clinical transformation of coronary heart disease. To analyze the clinical information of patients with transradial artery (PCI) performed in a representative city hospital in 2006 and 2011, and to calculate the annual data weighted separately. Results: 3 301 cases from 53 hospitals were analyzed. The number of patients admitted through radial artery PCI increased sevenfold from 2006 to 2011. Compared with 2006, the proportion of female patients and the average age in 2011 were higher than those in 2006, the number of patients with renal insufficiency [estimated glomerular filtration rate 60 ml/ (min 1.73m2)] and heart failure decreased (P 0.05), and the number of patients with coronary artery disease was decreased. However, the number of patients with three-vessel disease and left main lesion increased (P0.01). There was no significant change in the location distribution of PCI intervention between 2006 and 2011. The utilization rate of drug-eluting stents was significantly increased (P0.001), and that of antithrombotic and statins was significantly increased in 2011 (P 0.001). In 2006, the length of hospitalization in 2011 was 1 (0 715) days and 11 (7 / 14) days (P0.05). Compared with 2006, the incidence of bleeding at puncture site decreased significantly in 2011 (P0.01), and no significant change was found in other hospital adverse events. Conclusion: during the period from 2006 to 2011, the number of transradial PCI operations in urban hospitals of China increased rapidly, the clinical characteristics and treatment patterns of patients changed significantly, and the technique of transradial artery intervention therapy in China became more mature and routine.
【作者单位】：中国医学科学院北京协和医学院国家心血管病中心阜外医院国家心血管病临床研究中心心血管疾病国家重点实验室中国牛津国际医学研究中心;
【基金】：国家卫生和计划生育委员会卫生公益性行业科研专项(201202025,201502009) 国家科技部科技支撑计划(2015BAI12B01,2015BAI12B02) 高等学校学科创新引智计划(B16005)
【分类号】：R541.4

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