冠心病患者血清VEGF与Hp感染的关系
发布时间：2018-10-15 09:42
【摘要】：目的探讨冠心病(CHD)患者血清血管内皮细胞生长因子(VEGF)和幽门螺杆菌(Hp)感染的关系。方法选取CHD患者60例为观察组,抽取体检健康者60例为对照组检测VEGF和Hp-Ig G,统计组间结果。结果观察组Hp-Ig G感染阳性率显著高于对照组(P0.05),Hp感染阴性组纤维蛋白原(Fbg)、血超敏C反应蛋白(hs-CRP)及白细胞计数(P0.05)。观察组Hp-Ig G阳性血清VEGF及Hp-Ig G感染血清VEGF水平均显著低于对照组(P0.05)。结论 CHD患者血清VEGF水平与Hp感染联系密切,且用于VEGF及Hp-Ig G的检测也具有重要的价值,同时还可应用于CHD病情评估、诊断及其临床预后评估。
[Abstract]:Objective to investigate the relationship between serum vascular endothelial growth factor (VEGF) and Helicobacter pylori (Hp) infection in patients with coronary heart disease (CHD). Methods 60 patients with CHD were selected as observation group and 60 healthy persons as control group. The results of VEGF and Hp-Ig G were analyzed. Results the positive rate of Hp-Ig G infection in the observation group was significantly higher than that in the control group (P0.05). The blood hypersensitive C-reactive protein (hs-CRP) and white blood cell count (P05) of the fibrinogen (Fbg), positive group were significantly higher than those of the control group. The levels of Hp-Ig G positive serum VEGF and Hp-Ig G infection serum VEGF in the observation group were significantly lower than those in the control group (P 0.05). Conclusion the level of serum VEGF in patients with CHD is closely related to Hp infection, and it is also of great value in the detection of VEGF and Hp-Ig G. It can also be used in the evaluation, diagnosis and clinical prognosis evaluation of CHD.
【作者单位】： 新疆医科大学第六附属医院;新疆医科大学第一附属医院;新疆医科大学卫生事业发展改革研究所;
【基金】：新疆医科大学校级课题(No.HADR201602)
【分类号】：R541.4
，
本文编号：2272138
[Abstract]:Objective to investigate the relationship between serum vascular endothelial growth factor (VEGF) and Helicobacter pylori (Hp) infection in patients with coronary heart disease (CHD). Methods 60 patients with CHD were selected as observation group and 60 healthy persons as control group. The results of VEGF and Hp-Ig G were analyzed. Results the positive rate of Hp-Ig G infection in the observation group was significantly higher than that in the control group (P0.05). The blood hypersensitive C-reactive protein (hs-CRP) and white blood cell count (P05) of the fibrinogen (Fbg), positive group were significantly higher than those of the control group. The levels of Hp-Ig G positive serum VEGF and Hp-Ig G infection serum VEGF in the observation group were significantly lower than those in the control group (P 0.05). Conclusion the level of serum VEGF in patients with CHD is closely related to Hp infection, and it is also of great value in the detection of VEGF and Hp-Ig G. It can also be used in the evaluation, diagnosis and clinical prognosis evaluation of CHD.
【作者单位】： 新疆医科大学第六附属医院;新疆医科大学第一附属医院;新疆医科大学卫生事业发展改革研究所;
【基金】：新疆医科大学校级课题(No.HADR201602)
【分类号】：R541.4
，
本文编号：2272138
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