CTA评价主动脉瓣钙化对其功能影响的应用价值

发布时间：2018-11-06 09:00

【摘要】：目的探讨CTA评价主动脉瓣钙化对主动脉瓣功能的影响。方法搜集464例行CTA检查的患者资料,分为主动脉瓣膜钙化组61例和非钙化组403例。测量所有患者的收缩期末主动脉瓣开放角及主动脉瓣开口面积并测量瓣膜的厚度;记录主动脉瓣膜钙化的位置、钙化CT值及钙化面积。用Agataston方法定量分析钙化并计算钙化积分,分析钙化积分与各参数的关系。结果钙化瓣膜开放角小于非钙化瓣膜开放角,钙化瓣膜开放角与钙化位置有关。主动脉瓣钙化以后瓣及瓣膜根部多见。钙化瓣膜的厚度大于非钙化瓣膜的厚度,钙化组瓣膜开口面积小于非钙化的瓣膜开口面积。主动脉瓣各位置的钙化积分与主动脉瓣开放角、钙化积分与瓣膜开口面积及瓣膜厚度具有良好的关联性,且回归关系具有统计学意义。结论主动脉瓣钙化限制主动脉瓣的运动,以主动脉根部钙化为著。主动脉瓣钙化积分越高可能表明主动脉瓣开放残余角越大,主动脉瓣狭窄越重。主动脉瓣开放角的测量可能对瓣膜置换术有指导意义。
[Abstract]:Objective to evaluate the effect of aortic valve calcification on aortic valve function by CTA. Methods the data of 464 patients with CTA were divided into aortic valve calcification group (61 cases) and non calcification group (403 cases). The aortic valve opening angle and aortic valve opening area were measured and the aortic valve thickness was measured. The calcification location, calcification CT value and calcification area were recorded. Agataston method is used to analyze calcification quantitatively and calculate calcification integral, and the relationship between calcification integral and each parameter is analyzed. Results the open angle of calcified valve was smaller than that of non-calcified valve, and the opening angle of calcified valve was related to the location of calcification. After aortic valve calcification, valve and valve root are more common. The thickness of calcified valve was larger than that of non-calcified valve, and the opening area of calcified valve was smaller than that of non-calcified valve. The calcification integral of each position of aortic valve has good correlation with the open angle of aortic valve, and the calcification integral has good correlation with the area of valve opening and the thickness of valve, and the regression relationship is statistically significant. Conclusion Aortic valve calcification restricts the movement of aortic valve, especially aortic root calcification. The higher the calcification score of aortic valve may indicate that the larger the residual angle of aortic valve is, the more severe the aortic valve stenosis is. The measurement of aortic valve opening angle may be instructive for valve replacement.
【作者单位】：锦州医科大学中国人民解放军火箭军总医院研究生培养基地;
【分类号】：R542.5;R816.2

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