尼可地尔对高龄NSTEMI患者心功能和左室重构的影响

发布时间：2018-11-09 08:58

【摘要】：目的探讨尼可地尔对高龄非ST段抬高型急性心肌梗死患者心功能和左室重构的影响。方法选取高龄非ST段抬高型急性心肌梗死患者96例,随机分为观察组(48例)和对照组(48例),均行心肌梗死综合治疗。在综合治疗基础上,观察组口服尼可地尔5 mg/次,3次/d。两组均治疗3个月。观察两组治疗前后血清脑钠肽(BNP)、血管紧张素Ⅱ(AngⅡ)、左室射血分数(LVEF)、左室舒张末期内径(LVEDD)、舒张早期二尖瓣前叶峰流速(E峰)、舒张晚期二尖瓣前叶峰流速(A峰)以及E/A值。结果治疗3个月,观察组LVEF、E峰、E/A较对照组升高,LVEDD、A峰、BNP、AngⅡ较对照组降低,差异有统计学意义(P均0.05)。结论尼可地尔能有效保护高龄非ST段抬高型急性心肌梗死患者的心功能,预防左室重构。
[Abstract]:Objective to investigate the effects of nicorandil on cardiac function and left ventricular remodeling in elderly patients with non-ST segment elevation acute myocardial infarction. Methods 96 elderly patients with non ST segment elevation acute myocardial infarction were randomly divided into observation group (48 cases) and control group (48 cases). On the basis of comprehensive treatment, the observation group took Nicodil 5 times, 3 times a day. Both groups were treated for 3 months. Serum brain natriuretic peptide (BNP), angiotensin 鈪，

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