成年人蔬菜水果摄入与高血压关系的研究

发布时间：2018-11-11 17:33

【摘要】：目的:蔬菜水果摄入量与高血压发病风险之间的关系尚不明确。本文通过一个现况调查和一个Meta分析来探讨蔬菜和(或)水果以及分类蔬菜水果摄入量与高血压之间的关系。方法:在现况调查中,关于总的蔬菜水果摄入量与高血压之间关系的研究,数据来自美国国民健康和营养体格检查2007-2010年12002个成年人个体,采用单因素和多因素logistic回归分析评估从不、偶尔、有时、大多时候、经常摄入蔬菜或水果与高血压之间的关系;关于分类蔬菜水果摄入量与高血压之间关系的研究,数据来自美国国民健康和营养体格检查2003-2006年9992个成年人个体,采用卡方检验以及控制性别的Mantel-Haenszel(M-H)卡方检验分析分类蔬菜水果和高血压之间的关系。在Meta分析中,根据异质性的大小采用固定或随机效应模型合并相对危险度及其95%置信区间。结果:在现况调查中,多因素logistic回归结果显示:与最低剂量的水果、蔬菜摄入量相比,最高剂量的水果(OR=0.50;95%CI:0.29-0.87;P=0.014)、蔬菜(OR=0.73;95%CI:0.54-0.99;P=0.044)摄入量与高血压发病风险之间显著相关。控制性别后的M-H卡方检验结果显示:苹果(OR=0.75;95%CI:0.63-0.89;P=0.001)、凤梨(OR=0.82;95%CI:0.74-0.92;P=0.001)、生食的绿色蔬菜(OR=0.84;95%CI:0.76-0.92;P0.001)、黄瓜(OR=0.85;95%CI:0.75-0.96;P=0.007)与高血压之间呈有统计学意义的负相关关联。在Meta分析中,共纳入包括本次现况调查在内的26项研究,合并结果显示:蔬菜水果(RR=0.81;95%CI:0.74 0.89;I2=84.7%;P for heterogeneity0.001)以及水果(RR=0.71;95%CI:0.60 0.84;I2=69.3%;P for heterogeneity=0.001)摄入量的增加可显著降低高血压的发病风险,而蔬菜摄入量与高血压发病风险之间的关系无统计学意义(RR=0.90;95%CI:0.80 1.02;I2=54.1%;P for heterogeneity=0.042)。影响性分析结果显示,没有任意一项研究对蔬菜水果、水果、蔬菜摄入量与高血压之间相对危险度的合并效应值有统计学意义的影响。结论:水果摄入量的增加可能降低高血压的发病风险。在分类的蔬菜水果中,苹果、凤梨、生食的绿色蔬菜、黄瓜可能与高血压发病风险的降低相关。
[Abstract]:Objective: the relationship between the intake of fruits and vegetables and the risk of hypertension is unclear. The relationship between vegetable and / or fruit intake and hypertension was investigated by a situational survey and a Meta analysis. Methods: a study of the relationship between total vegetable and fruit intake and hypertension was conducted in the current survey, with data from 1, 200 adults for the National Health and Nutrition physical examination of the United States from 2007 to 2010. Univariate and multivariate logistic regression analysis was used to assess the relationship between never, occasionally, and most of the time, frequent intake of vegetables or fruits and hypertension; The study on the relationship between vegetable and fruit intake and hypertension was based on data from the United States National Health and Nutrition physical examination 2003-2006 for 9,992 adults. The relationship between vegetables and fruit and hypertension was analyzed by chi-square test and Mantel-Haenszel (M-H) chi-square test. In Meta analysis, the relative risk and its 95% confidence interval are combined with fixed or random effect models according to the size of heterogeneity. Results: in the current survey, the results of multivariate logistic regression showed that the highest dose of fruit (OR=0.50;95%CI:0.29-0.87;P=0.014) and vegetable (OR=0.73;) were higher than the lowest dose of fruit and vegetable intake. 95 CI: 0.54-0.99 P0. 044) intake was significantly associated with the risk of hypertension. The M-H chi-square test showed that: OR=0.75;95%CI:0.63-0.89;P=0.001, OR=0.82;95%CI:0.74-0.92; There was a significant negative correlation between green vegetables (OR=0.84;95%CI:0.76-0.92;P0.001) and cucumber (OR=0.85;95%CI:0.75-0.96;P=0.007) and hypertension. In the Meta analysis, 26 studies, including the current survey, were included. The combined results showed that vegetables and fruits (RR=0.81;95%CI:0.74 0.89 I _ 2i _ 2i _ 2 ~ 84.7p for heterogeneity0.001) and RR=0.71; The increase of intake of 95%CI:0.60 0.84% I2G 69.3% P for heterogeneity=0.001 significantly reduced the risk of hypertension, while the relationship between vegetable intake and risk of hypertension was not statistically significant (RR=0.90;). 95%CI:0.80 1. 02 I 2 + 54.1% P for heterogeneity=0.042. The results of impact analysis showed that none of the studies had a significant effect on the combined effect value of the relative risk between vegetables and fruits, vegetable intake and hypertension. Conclusion: the increase of fruit intake may reduce the risk of hypertension. In classified vegetables and fruits, apples, pineapples, raw green vegetables, and cucumbers may be associated with reduced risk of hypertension.
【学位授予单位】：青岛大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R544.1

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