温阳利水活血汤联合西药治疗慢性收缩性心力衰竭阳虚血瘀证的临床疗效观察

发布时间：2018-11-11 20:06

【摘要】：目的探讨温阳利水活血汤联合西药治疗慢性收缩性心力衰竭阳虚血瘀证的临床疗效。 方法选取确诊为慢性收缩性心衰,且辨证为阳虚血瘀证的患者60例,按入院先后随机分为治疗组及对照组各30例。两组均采用无差别的西医治疗,治疗组另加温阳利水活血汤治疗。观察治疗前和治疗14天后患者的中医证候积分改善情况、心功能分级、NT-proBNP(N末端脑钠肽前体)、LVEF(左室射血分数)变化。 结果(1)治疗后两组在中医证候积分改善方面,治疗组总有效率为86.66%,对照组总有效率为76.66%,两组疗效对比,P0.05,治疗组疗效优于对照组。 (2)两组血浆NT--proBNP及LVEF治疗前后对比均明显改善,P0.05,治疗后两组血浆NT--proBNP及LVEF对比p0.05,治疗组疗效优于对照组。 (3)治疗组心功能分级改善为93.33%,对照组为70.00%,两组对比,P0.05,治疗组优于对照组。 结论温阳利水活血汤联合西药治疗辨证为阳虚血瘀证的慢性心力衰竭有较好的临床疗效,且安全性较高。
[Abstract]:Objective to investigate the clinical effect of Wenyang Lishui Huoxue decoction combined with western medicine in the treatment of chronic systolic heart failure with yang deficiency and blood stasis syndrome. Methods Sixty patients with chronic systolic heart failure and syndrome differentiation of yang deficiency and blood stasis were randomly divided into treatment group (n = 30) and control group (n = 30). Both groups were treated by western medicine without difference, and the treatment group was treated with warming Yang Li Shui Huo Xue Tang. The improvement of TCM syndromes score, cardiac function grading and NT-proBNP (left ventricular ejection fraction) of N-terminal brain natriuretic peptide precursor (), LVEF () were observed before and 14 days after treatment. Results (1) after treatment, the total effective rate was 86.66 in the treatment group and 76.66 in the control group. The curative effect of the treatment group was better than that of the control group (P 0.05). (2) the plasma NT--proBNP and LVEF of the two groups were significantly improved before and after treatment, P 0.05. After treatment, the plasma NT--proBNP and LVEF of the two groups were compared with that of the control group. The curative effect of the treatment group was better than that of the control group. (3) the improvement of cardiac function grade in the treatment group was 93.33 and that in the control group was 70.00.The difference between the two groups was P0.05. the treatment group was superior to the control group. Conclusion Wenyang Lishui Huoxue decoction combined with western medicine in treating chronic heart failure with syndrome differentiation of yang deficiency and blood stasis has better clinical effect and higher safety.
【学位授予单位】：湖南中医药大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R541.6

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