人格特征与血脂水平对心绞痛患者心肌酶的影响（英文）

发布时间：2018-11-14 11:07

【摘要】：目的:探讨人格特征和血脂水平对心绞痛患者心肌酶的影响。方法:采用调查法对45例不稳定型心绞痛患者、60例稳定型心绞痛患者和50例健康人进行A型和D型人格问卷检测,同时检测血脂、肌钙蛋白(ICTNI)、肌酸激酶同工酶(CKMB)、乳酸脱氢酶(LDH)及乳酸脱氢酶1(LDH_1)水平。结果:与稳定型心绞痛和健康对照组比较,不稳定型心绞痛患者血清高密度脂蛋白水平显著降低;A型人格和D型人格得分、血清心肌酶水平显著升高。血清高密度脂蛋白水平与LDH_1显著负相关,时间紧迫感与血清LDH、LDH_1水平显著正相关,竞争和敌意与血清LDH水平显著正相关;D型人格特征与血清心肌酶水平无显著相关。高密度脂蛋白、时间紧迫感、竞争和敌意对心肌酶的效应值分布在0.125-0.039之间,为中等和较小效应值。结论:血清高密度脂蛋白、时间紧迫感和敌意与冠心病心肌损伤密切相关。
[Abstract]:Objective: to investigate the effects of personality and lipid levels on myocardial enzymes in patients with angina pectoris. Methods: 45 patients with unstable angina pectoris, 60 patients with stable angina pectoris and 50 healthy persons were investigated with type A and D personality questionnaires. Blood lipid and troponin (ICTNI), creatine kinase isoenzyme (CKMB), were also detected. Lactate dehydrogenase (LDH) and lactate dehydrogenase 1 (LDH_1) levels. Results: compared with stable angina pectoris and healthy control group, the serum HDL level of unstable angina pectoris patients was significantly lower, and the scores of type A personality and D personality, serum myocardial enzyme level were significantly increased. Serum HDL level was negatively correlated with LDH_1, time urgency was positively correlated with serum LDH,LDH_1 level, competition and hostility were positively correlated with serum LDH level. There was no significant correlation between type D personality traits and serum myocardial enzyme level. The effects of high density lipoprotein (HDL), time urgency, competition and hostility on myocardial enzymes ranged from 0.125-0.039, which were moderate and small. Conclusion: high density lipoprotein (HDL), time urgency and hostility are closely related to myocardial injury in coronary heart disease.
【作者单位】：山东大学临床医学院神经病学系;山东大学齐鲁医院心内科;美国休斯敦大学心理学系;山东大学基础医学院医学心理学系;
【基金】：济南市高校创新基金(201202227)
【分类号】：R541.4

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