中老年人群体脂分布与平均血小板体积之间的相关性

发布时间：2018-11-23 10:54

【摘要】：目的探讨中老年人群体脂分布与平均血小板体积(MPV)之间的相关性。方法选取200例健康查体的中老年人,分成男子组103例和女子组97例。所有个体均通过人体成分分析仪测量内脏脂肪量(VFV)、皮下脂肪量(SFV)、全自动血液细胞分析仪检测血小板相关参数。结果男子组VFV高于女子组(3.17±0.84 vs 2.30±0.94 kg,P0.001),SFV低于女子组(15.56±3.49 vs 17.69±4.82 kg,P0.001),MPV存在差异(P=0.003)。男子组MPV与VFV(r=0.539,P0.001)、空腹血糖(r=0.263,P=0.004)、体重指数(r=0.269,P=0.003)、收缩压(SBP,r=0.344,P0.001)及舒张压(DBP,r=0.316,P=0.001)呈正相关,但仅VFV与MPV存在明显的联系;女子组MPV与年龄(r=0.242,P0.009)、SFV(r=0.502,P0.001)、空腹血糖(r=0.208,P=0.021)、SBP(r=0.286,P=0.002)呈正相关,而与高密度脂蛋白胆固醇(HDL-C,r=-0.242,P=0.008)、载脂蛋白A1(Apo A1,r=-0.240,P=0.009)呈负相关,但仅年龄、SFV与MPV存在明显的联系。结论中老年健康人群体脂分布存在性别差异,男子组MPV与VFV、空腹血糖、体重指数、SBP及DBP呈正相关,VFV是影响MPV的独立危险因素;女子组MPV与年龄、SFV、空腹血糖、SBP呈正相关,而与HDL-C、Apo A1呈负相关,SFV是影响MPV的独立危险因素。
[Abstract]:Objective to investigate the correlation between lipid distribution and mean platelet volume (MPV) in middle aged and elderly population. Methods 200 cases of middle and old people were divided into male group (103 cases) and female group (97 cases). The visceral fat quantity (VFV),) subcutaneous fat quantity (VFV),) was measured by human component analyzer. The platelet related parameters were measured by (SFV), automatic blood cell analyzer. Results the VFV of male group was higher than that of female group (3.17 卤0.84 vs 2.30 卤0.94 kg,P0.001), SFV), which was lower than that of female group (15.56 卤3.49 vs 17.69 卤4.82 kg,P0.001), MPV) (P0. 003). Men's MPV and VFV (rn 0.539g P0.001), fasting blood glucose (rn 0.263), body mass index (BMI) 0.269g P0. 003, systolic blood pressure (SBP,r=0.344,P0.001) and diastolic blood pressure (DBP,r=0.316,) P0. 001) was positively correlated, but only VFV was significantly correlated with MPV. In female group, MPV was positively correlated with age (r = 0.242), fasting blood glucose (r = 0.208) and high density lipoprotein cholesterol (HDL-C,). There was a negative correlation between apolipoprotein A1 (Apo A1A1-0.240 P0. 009) and apolipoprotein A1, but only in age. There was a significant correlation between SFV and MPV. Conclusion there is a gender difference in body fat distribution in healthy middle-aged and elderly people. MPV is positively correlated with fasting blood glucose, body mass index, SBP and DBP in male group. VFV is an independent risk factor for MPV. MPV was positively correlated with age, SFV, fasting blood glucose and SBP, but negatively correlated with HDL-C,Apo A1. SFV was an independent risk factor for MPV.
【作者单位】：东营市广饶县大码头西刘桥卫生院;
【基金】：山东省医药卫生科技发展计划项目(No.2013WS0031)
【分类号】：R54

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