低骨密度与非糖尿病性冠心病患者冠状动脉病变的相关性

发布时间：2019-05-15 17:48

【摘要】：目的探讨低骨密度(包括骨质疏松与骨量减少)与非糖尿病性冠心病患者冠状动脉病变严重程度的相关性。方法入选156例因胸痛入院的非糖尿病患者,收集一般临床资料和常规检验指标结果,采用冠状动脉造影明确冠心病,按照冠状动脉病变血管数进行分组:无冠状动脉病变组(非冠心病组)、单支病变组、双支病变组、三支病变组。64排螺旋CT扫描机测定冠状动脉钙化积分,按冠状动脉钙化积分分组:无钙化组(10分)、轻度钙化组(10~100分),中度钙化组(100~400分)、重度钙化组(400分)。双能X线骨密度仪测定骨密度水平,根据检查结果分为骨质疏松组、骨量减少组和骨量正常组,比较三组间冠状动脉病变程度的差异。结果随着冠状动脉狭窄程度和钙化程度的加重,低骨密度发病率呈升高趋势。骨量减少组和骨质疏松组冠状动脉狭窄程度和钙化程度明显高于骨量正常组,三组间比较有统计学差异(P0.01)。结论低骨密度可能是血糖正常的冠心病患者冠状动脉狭窄及钙化程度的独立危险因素。
[Abstract]:Objective to investigate the correlation between low bone mineral density (including osteoporosis and bone mass reduction) and the severity of coronary artery disease in patients with non-diabetic coronary heart disease. Methods 156 non-diabetic patients admitted to hospital because of chest pain were enrolled in this study. the general clinical data and the results of routine test were collected and coronary angiography was used to determine coronary heart disease. According to the number of coronary artery lesions: no coronary artery disease group (non-coronary heart disease group), single vessel disease group, double vessel disease group, three vessel disease group. Coronary artery calcification score was measured by 64-slice spiral CT scanner. According to coronary artery calcification score, non-calcification group (10 points), mild calcification group (10 鈮，

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