聚维酮碘冲洗联合左氧氟沙星滴眼预防白内障患者术后感染的疗效研究

发布时间：2018-02-10 22:18

本文关键词： 聚维酮碘结膜囊左氧氟沙星白内障术后感染疗效　出处：《中华医院感染学杂志》2015年12期 　论文类型：期刊论文

【摘要】：目的探讨聚维酮碘稀释液结膜囊冲洗联合左氧氟沙星滴眼预防白内障术后感染疗效,并观察和分析其预后,为临床预防和降低白内障术后感染提供依据。方法选择2012年7月-2015年3月接受白内障手术患者364例、509只眼,按照单双号随机分为对照组和观察组,对照组患者180例、244只眼,术前应用左氧氟沙星滴眼进行预防;观察组患者184例、265只眼,应用聚维酮碘稀释液结膜囊冲洗联合左氧氟沙星滴眼进行预防,评估两组患者冲洗前、后及术后第2天细菌培养结果及术后不良反应。结果观察组患者冲洗后及术后第2天细菌阳性率均为0.75%,均低于对照组5.33%和6.15%,差异有统计学意义(P0.05);观察组患者术后总不良反应发生率为0.75%,低于对照组3.28%,差异有统计学意义(P0.05)。结论聚维酮碘稀释液结膜囊冲洗联合左氧氟沙星滴眼预防白内障术后感染具有较好的临床疗效,能够减少细菌培养阳性率,降低患者不良反应发生率。
[Abstract]:Objective to investigate the effect of infection with povidone iodine diluent conjunctival sac washing combined with levofloxacin eye drops for preventing after cataract surgery, and to observe and analyze the prognosis, provide the basis for clinical prevention and reduce the infection after cataract surgery. Methods from July 2012 -2015 year in March 364 cases underwent cataract surgery, 509 eyes were divided into, according to the control group and the observation group, 180 cases of control group were 244 Cases, preoperative application of levofloxacin for prevention; observation of 184 cases of patients, 265 eyes, povidone iodine diluent conjunctival sac irrigation combined with levofloxacin eye drops to prevent flushing, evaluation of two groups of patients before and after surgery. After second days of bacterial culture results and adverse reaction after operation. The patients in the observation group after washing and after second days the positive rate of bacteria was 0.75%, 5.33% and 6.15% were lower than the control group, the difference was statistically significant (P0.05); observation group Patients with postoperative adverse reaction rate was 0.75%, 3.28% lower than the control group, the difference was statistically significant (P0.05). Conclusion the infection has better clinical efficacy of povidone iodine diluent conjunctival sac washing combined with levofloxacin eye drops for preventing after cataract surgery can reduce the bacterial culture positive rate, reduce the incidence of adverse reactions in patients.

【作者单位】：浙江省海盐县人民医院眼科;湖州市第一人民医院眼科;
【基金】：浙江省卫计委医药卫生科技基金资助项目(2015ZHB011)
【分类号】：R779.66

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