良性阵发性位置性眩晕患者前庭诱发肌源性电位的特点

发布时间：2018-03-24 11:01

本文选题：良性阵发性位置性眩晕　切入点：前庭诱发肌源性电位　出处：《西安交通大学学报(医学版)》2014年01期

【摘要】：目的探讨良性阵发性位置性眩晕(BPPV)患者前庭诱发肌源性电位(VEMPs)的临床特征。方法对67例BPPV患者及19例(38耳)年龄、性别与之匹配的健康人进行颈肌前庭诱发肌源性电位(cVEMP)及眼肌前庭诱发肌源性电位(oVEMP)测试,分析对比VEMPs的引出率及各参数指标。结果 oVEMP在病例组患侧的引出率为43.3%、健侧为41.8%,对照组为71.1%;患侧与健侧比较差异无统计学意义(P0.05),患侧、健侧与对照组比较差异均有统计学意义(P0.01)。cVEMP在病例组患侧的引出率为62.7%、健侧为61.2%,对照组为84.2%;患侧与健侧比较差异无统计学意义(P0.05),患侧、健侧与对照组间比较差异均有统计学意义(P0.05)。oVEMP引出率较cVEMP引出率更低(P0.05)。病例组患侧、健侧及对照组间oVEMP、cVEMP的阈值、各波潜伏期、振幅对比均无统计学差异(P0.05)。结论 BPPV患者无论健侧还是患侧,其oVEMP和cVEMP引出率均显著下降,且以oVEMP降低为著,提示BPPV患者的耳石器,尤其是椭圆囊机能受损明显;引出VEMPs波形的BPPV患者,无论oVEMP还是cVEMP,其波形(参数)基本正常。
[Abstract]:Objective to investigate the benign paroxysmal positional vertigo (BPPV) in patients with vestibular evoked myogenic potentials (VEMPs) of the clinical features. Methods 67 cases of BPPV and 19 cases (38 ears) age and gender matched healthy people were cervical vestibular evoked myogenic potentials (cVEMP) and ocular vestibular evoked myogenic potential (oVEMP) test, comparative analysis of the positive rates of VEMPs and parameters. The results of oVEMP in cases with side of the extraction rate was 43.3%, the healthy side was 41.8%, the control group was 71.1%; there was no significant difference and the contralateral side (P0.05), ipsilateral and contralateral compared with the control group there was statistically significant (P0.01.CVEMP) in case group ipsilateral extraction rate was 62.7%, the healthy side was 61.2%, the control group was 84.2%; there was no significant difference and the contralateral side (P0.05), ipsilateral, contralateral and control group differences were statistically significant (P0.05).OVEMP extraction rate compared with cVEMP Extraction rate is lower (P0.05). Cases of ipsilateral, contralateral and control groups oVEMP, cVEMP threshold, latency, amplitude comparison showed no statistical difference (P0.05). Conclusion BPPV patients were treated with either contralateral or ipsilateral, its oVEMP and cVEMP positive rates were significantly decreased, and the lower is oVEMP, suggesting that BPPV patients with ear stone, especially the utricular function was impaired; leads VEMPs waveform with BPPV, both oVEMP and cVEMP, the waveform (parameters) is essentially normal.

【作者单位】：西安交通大学医学院第二附属医院耳鼻咽喉头颈外科病院、耳病研究所;日本东京医疗中心感觉器官研究所;
【基金】：科技部“十一五”科技支撑计划项目(No.2007BAI18B13) 中央高校基本科研业务费专项资金(No.2012jdhz13) 陕西省国际科技合作重点项目(No.2013KW-28) 西安市科技攻关项目(No.SF1315(1)) 西安交通大学医学院第二附属医院2011年新技术新疗法基金(No.2011015)~~
【分类号】：R764

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