远视眼与近视眼角膜生物力学研究及眼压的比较

发布时间：2018-03-26 00:52

本文选题：中央角膜厚度　切入点：角膜滞后量　出处：《眼科新进展》2014年10期

【摘要】：目的比较远视眼与近视眼角膜生物力学参数和眼压的差异。方法分别选取远视眼与近视眼各60眼,应用眼反应分析仪测量角膜生物力学的指标:角膜滞后量和角膜阻力因子量,模拟Goldmann眼压,角膜补偿眼压。对远视组和近视组的角膜屈光力、中央角膜厚度及角膜生物力学相关参数进行t检验;对角膜生物力学特性的影响因素进行相关性分析;对中央角膜厚度与眼压的关系进行Pearson相关分析。结果远视组与近视组之间角膜屈光力差异有显著统计学意义(t=-4.103,P0.01)。仅中央角膜厚度与角膜滞后量和角膜阻力因子量呈显著正相关(r=0.637、0.519,均为P0.01)。中央角膜厚度与非接触眼压计测得的眼压和模拟Goldmann眼压均呈正相关(r=0.428、0.406,均为P0.01),与角膜补偿眼压不相关(r=0.075,P=0.466)。角膜屈光力与非接触眼压计测得的眼压呈正相关(r=0.283,P0.01),与模拟Goldmann眼压和角膜补偿眼压无相关性(r=0.186、0.117,P=0.067、0.251)。结论角膜的生物力学参数主要与角膜厚度呈正相关,不受眼屈光状态影响。
[Abstract]:Objective to compare the corneal biomechanical parameters and intraocular pressure (IOP) between hyperopia and myopia. The corneal refractive power, central corneal thickness and corneal biomechanical parameters in hyperopic and myopic groups were tested by t test, and the factors affecting corneal biomechanical properties were analyzed. The correlation between central corneal thickness and intraocular pressure (IOP) was analyzed by Pearson. Results there was significant difference in corneal refractive power between hyperopia group and myopia group (P 0.01). Only the central corneal thickness was correlated with corneal lag and corneal resistance factor. The intraocular pressure measured by the central corneal thickness and the non-contact IOP was positively correlated with the simulated Goldmann IOP (P 0.01), and was not related to the corneal compensatory intraocular pressure. The corneal refractive power and the intraocular pressure measured by the non-contact IOP were positively correlated with the corneal compensatory intraocular pressure. There was a positive correlation between Goldmann IOP and corneal compensated intraocular pressure. Conclusion the biomechanical parameters of the cornea were positively correlated with corneal thickness, and the corneal biomechanical parameters were positively correlated with the corneal thickness, but not with the simulated intraocular pressure (IOP) and corneal compensatory intraocular pressure (CPP). Not affected by the refractive state of the eye.
【作者单位】：首都医科大学附属北京同仁医院北京同仁眼科中心北京市眼科学与视觉科学重点实验室;
【分类号】：R778.1

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