眼科患者术后抗菌药物治疗对创口愈合的作用研究

发布时间：2018-04-17 07:34

本文选题：眼科手术 + 抗菌药物　；参考：《中华医院感染学杂志》2015年12期

【摘要】：目的研究眼科患者术后使用抗菌药物治疗对创口愈合的影响,为临床诊治提供理论依据。方法选取2010年4月-2014年4月医院收治的80例接受眼科手术患者,随机抽取40例作为试验组(抗感染组),其余40例患者作为对照组(非抗感染组),用相同手术方法进行眼科手术,缝合切口后,试验组患者给予氨苄西林进行抗感染治疗,而对照组则不使用抗菌药物进行预防,对比两组患者3~8d切口愈合情况。结果试验组患者3d愈合共14例,3~8d愈合共21例,8d愈合共5例;而对照组患者3d愈合共5例,3~8d愈合共13例,8d愈合共22例,试验组患者愈合时间明显比对照组短,两组比较差异有统计学意义(P0.05);试验组有效率为92.5%,平均愈合时间为(3.8±0.4)d;对照组有效率为45.0%,平均愈合时间为(7.2±0.5)d;两组比较差异有统计学意义(P0.05);两组患者在术后均出现疼痛、红肿等感染症状,但相比于未使用抗菌药物预防术后感染的对照组,试验组患者感染症状明显减轻。结论眼科术后使用抗菌药物对于创口愈合有明显作用。
[Abstract]:Objective to study the effect of antimicrobial therapy on wound healing in patients with ophthalmology, and to provide theoretical basis for clinical diagnosis and treatment.Methods from April 2010 to April 2014, 80 patients undergoing ophthalmic surgery were randomly selected as the experimental group (anti-infection group) and the other 40 patients as the control group (non-anti-infection group).After suture, the patients in the experimental group were treated with ampicillin for antiinfective therapy, while the control group was not prevented by antibiotics. The healing of the incision was compared between the two groups in 3 and 8 days.Results in the trial group, 14 cases were healed on 3 days, 21 cases were healed on the 8th day, 5 cases were healed on the 8th day, while in the control group, 5 cases were healed on the 3rd day, 13 cases were healed on the 8th day, 22 cases were healed. The healing time of the patients in the trial group was significantly shorter than that in the control group, and the healing time of the patients in the trial group was significantly shorter than that in the control group.The effective rate of the two groups was 92.5 and the average healing time was 3.8 卤0.4 days. In the control group, the effective rate was 45.0 and the average healing time was 7.2 卤0.5 days.Infection symptoms such as redness and swelling were significantly alleviated in the experimental group as compared with the control group which did not use antimicrobial agents to prevent postoperative infection.Conclusion the use of antimicrobial agents has obvious effect on wound healing after ophthalmic operation.
【作者单位】：奉化市人民医院眼科;
【基金】：浙江省科技厅研究基金资助项目(201309231)
【分类号】：R779.6

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